Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 1017 for “"ROS"”.
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ROS regulation of axonal mitochondrial transport
… also a major source of reactive oxygen species (ROS) production. To maintain cellular function and survival in neurons, mitochondria are transported along axons, and accumulate in regions with high demand for their functions. Oxidative stress and abnormal mitochondrial axonal transport are …
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Targeting Mitochondrial ROS Production in Kidney Transplantation
… of mitochondrial reactive oxygen species (ROS) production, thought to initiate many of the downstream pathways resulting in IRI, has been described. This mechanism has identified a number of new therapeutic targets within mitochondria, including the respiratory complex succinate …
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Dynamics and implications of ROS in marine systems
The reactive oxygen species (ROS), superoxide and hydrogen peroxide, play critical roles across diverse marine ecosystems, influencing redox chemistry and organismal health. The distribution and concentration of these compounds in the oceans may serve as important controls for various …
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ROS and SIK regulation of Stress-Induced Sleep
… demand such as stress, reactive oxygen species (ROS) levels serve as a signal for sleep need. Using C. elegans as a model of KIN-29/SIK- regulated sleep, I tested this hypothesis in the following chapters. Chapter 1 characterizes SIK proteins in the context of sleep, gives an overview of redox …
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Critical role of ROS in capsaicin-induced hyperalgesia
… studies indicate that reactive oxygen species (ROS) are critically involved in persistent pain primarily through spinal mechanisms, thus suggesting ROS involvement in central sensitization. To investigate ROS involvement in central sensitization, the effects of ROS scavengers and donors on pain …
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Dynamics and Implications of ROS in Marine Systems
The reactive oxygen species (ROS), superoxide and hydrogen peroxide, play critical roles across diverse marine ecosystems, influencing redox chemistry and organismal health. The distribution and concentration of these compounds in the oceans may serve as important controls for various …
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The Role of NADPH Oxidase in ROS Mediated Differentiation
… by an increase in reactive oxygen species (ROS), which induces a conformational change in Nucleoredoxin preventing its ability to bind and inhibit Dishevelled. This in turn positively impacts on the WNT/β- catenin signaling pathway leading to differentiation. The source of endogenous ROS …
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A Robot Operating System (ROS) based humanoid robot control
… used in this research. Robot operating System (ROS) and its libraries, as well as Python Script and its libraries have been developed and incorporated into the BBB. This fortified BBB intelligence providing component is then transplanted into the structure of the Robotis Bioloid humanoid robot, …
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Ros-Drill Automation: Visual Feedback Control And Rotational Motion Tracking
… We focus on a relatively recent procedure called Ros-Drill<sup>©</sup> (rotationally oscillating drill), of which the early versions have already been effectively utilized for the mice. In the first part, we present a procedure to automate a critical part of the operation: <em>initiation of the …
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Novel Cancer Therapeutics, the Generation of ROS, and Cell Survival
… An effect abolished by the addition of the ROS-quenchers, NAC and Trolox. Collectively, these findings argue that geldanamycins may not be a viable therapy for HCC treatment and that 17-AAG toxicity in primary hepatocytes may be, at least upon initial drug exposure, due to ROS generation and …
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Towards a Prototype Platform for ROS Integrations on a Ground Robot
… demonstrate a prototype robot platform on which ROS integrations could be explored. With observations of features and requirements of existing industrial and service mobile ground robots, a platform was designed and outfitted with appropriate components to enable the most common …
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Investigating complex I dynamics and ROS production in ischaemia-reperfusion injury
… and causes formation of reactive oxygen species (ROS) when oxygen is resupplied. Complex I is a major source of ROS in IR injury, but also in physiological ROS signalling. The enzyme can produce ROS via reverse electron transfer (RET), which is driven by a large protonmotive force (∆p) in …
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An analysis on controlling humanoid robot arm using Robot Operating System (ROS)
… the robotic arm using Robot Operating System (ROS) platform. ROS is preferred since it is modular, simple and easy to use tools for development, it provides good hardware support, lots of algorithms are implemented together as package, etc.
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Mitochondrial respiratory defects induces claudin 1 expression via ROS-mediated HSF1 activation
… level, accompanied by increase in mitochondrial ROS production. Treatment of H2O2 directly induced Cln-1 expression, implying that Cln-1 induction was mediated by mitochondrial ROS. Interestingly, Cln-1 promoter region (-2700bp ~ +300bp) contained transcription factor binding site Heat Shock …
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CAVEOLAE AS SPATIO-TEMPORAL COMPARTMENTS FOR ROS/RNS GENERATION AND NITROXIDATIVE STRESS SIGNALING
… excessive production of reactive oxygen (ROS) and nitrogen species (RNS), peroxynitrite, is implicated in the development of vascular pathologies. Our previous studies showed that both NADPH oxidase enzyme complexes and eNOS localize to endothelial caveolae microdomains. Additionally, …
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Mitophagy-Mediated Regulation of ROS Homeostasis During HSC Activation Contributes to Cell Fate
… show high levels of reactive oxygen species (ROS) and a higher proportion of cycling cells at steady state. Mitophagy-defective HSCs aberrantly accrued ROS only upon HSC activation, sensitizing them to apoptosis, cell cycle delay, and/or differentiation, ultimately resulting in failure of the …
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Reactive Oxygen Species (ROS) Triggered Delivery System for the Treatment of Diabetic Retinopathy
… used conjugation of reactive oxygen species (ROS) sensitive moiety which triggered the release of incorporated drugs in response to ROS in DR. Beta-cyclodextrin was conjugated with a ROS sensitive moiety (Ox-β-cyclodextrin), 4-(hydroxymethyl) phenylboronic acid pinacol ester (PBAP) and was …
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