Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"ROM/RCM"”.
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Novel Polycyclic Benzannulated Indole Scaffolds via Indole Aryne Cycloaddition, Pd (0)-Catalyzed Cross-coupling and ROM/RCM methodologies: Their Applications to Library Development and Drug Discovery
… Indole motifs represent one of the most prominent privileged structures and are ubiquitous in natural products and pharmaceutical compounds. A variety of fused heterocyclic structures will be designed, resulting in novel polycyclic frameworks with virtually no representation in the …
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“Trans-Positioning” Carbons within Strained Caged Bicyclic(s): ROM/RCM (Ring-Opening/Ring-Closing) Metathesis and Dieckmann/Retro-Dieckmann Condensation Routes to a Cis-Decalin Infrastructure
<p>This dissertation describes methodology work involving a “Trans-Positioning” motif engaging strategically positioned carbons within a strained bi-carbocyclic core and on a tethered free-dangling hydrocarbon chain ultimately for skeletal rearrangement. Trans-alkenylation and trans-acylation …