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Showing 1 to 1 of 1 for “"RNase H function inhibitors"”.

  1. Characterization of the mechanism of action of new HIV-1 reverse transcriptase-associated ribonuclease H inhibitors

    … to be exploited, as. HIV-1 RT combines two functions essential for viral replication: DNA polymerase, synthesis DNA either in a RNA dependent (RDDP) or DNA dependent (DDDP) manner, and Ribonuclease H (RNase H) . The RNase H activity catalyzes highly specific hydrolytic events on the RNA …

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