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Showing 1 to 1 of 1 for “"RNF138"”.
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Regulation of Rad51D In Homologous Recombination Dna Repair by Alternative Splicing and Ubiquitin Modification
… work focused on an E3 ubiquitin ligase named RNF138. Interestingly, RNF138 specifically interacted with and stimulated RAD51D ubiquitination. Consistent with a role during HR, reduced RNF138 expression conferred heightened sensitivity to DNA damaging agents and increased levels of chromosome …