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Showing 1 to 1 of 1 for “"RNF126"”.
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Taming a Potent Mutator: Identification and Characterization of Novel Mechanisms of Regulating Antibody Diversification in B-Lymphocytes
… in the screen, RING Finger Protein 126 (RNF126). In vitro studies revealed that RNF126 is a bona fide AID binding partner and, in addition, acts as an E3 ubiquitin ligase, modifying AID with the addition of a single ubiquitin moiety. Further, a conditional knockout model of RNF126 was …