Global ETD Search
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Showing 1 to 7 of 7 for “"RND efflux"”.
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Cloning and characterization of AdeMNO RND efflux pump of Acinetobacter baumannii
… the role of Resistance-Nodulation-cell Division (RND) efflux pumps in the antibiotic resistance mechanism of A. baumannii. Expression of six different RND pumps was analyzed in clinical isolates of A. baumannii. A novel RND family pump, AdeMNO, was found to be present in a majority of isolates. …
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Investigating The Functional Relationships Of RND Efflux Pumps In Methicillin Resistant Staphylococcus Aureus
The RND superfamily of efflux pumps plays vital roles in the intrinsic defence mechanisms of bacterial pathogens. The staphylococci have two genes encoding RND transporters; farE, which promotes efflux of antimicrobial fatty acids, and an uncharacterized gene we have named femT. Although RND pumps …
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Impact of environmental conditions on expression levels of resistance-nodulation-division (RND) efflux pumps and outer membrane porins in Acinetobacter baumannii
… such as Resistance-Nodulation-Cell Division (RND) efflux pumps and outer membrane proteins, is regarded to be amongst the most important strategies in the arsenal of this pathogen. Despite considerable efforts being dedicated in the attempt to understand the underlying mechanisms in the …
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Analysis of resistance nodulation division efflux pumps in Acinetobacter baumannii
… expressed resistance nodulation division (RND) efflux pump was adeFGH. A collection of A. baumannii isolates from the environment showed decreased susceptibility to at least three antibiotics and expression of three RND efflux pumps (adeFGH, adeABC, adeIJK). From the clinical collection two …
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Genetic mechanisms contributing to antimicrobial resistance: gene repression in Mycobacterium, gene transfer in Salmonella, and phage sensitivity in Escherichia
… studies to investigate the regulation of efflux pump expression in Mycobacterium intracellulare, regulation mechanisms of natural competence in Salmonella Typhimurium, and phage therapy of Enterohemorrhagic Escherichia coli serogroup O157:H7. A recent study showed specific mutations in the …
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The Role of Multidrug Efflux Pumps in the Stress Response of Pseudomonas aeruginosa to Organic Contamination
… damage due to the upregulation of multidrug efflux pumps. Further study of this PCP-mediated induction of efflux pumps revealed a simultaneous increase in antibiotic resistance. It was discovered that the resistance nodulation-cell division (RND) efflux pump, MexAB-OprM, in particular is …
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Single copy gene expression system as a tool for the purification of membrane proteins from Pseudomonas aeruginosa
… contributors to this resistance is the active efflux of antibiotics from the cell, primarily by action of the Resistance Nodulation Division (RND) family of efflux pumps. These pumps are composed of three proteins; an inner membrane RND pump, a periplasmic membrane fusion adaptor protein, and …