Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"RNAbinding"”.
-
Functional characterization of the RNA binding protein RALY
… the basis for the high variety of cells. The RNAbinding proteins (RBPs) play crucial roles in this variability by regulating many steps of biological processes regarding RNA metabolism. The heterogeneous nuclear ribonucleoproteins (hnRNPs) belong to big family of RBPs involved in many aspects …
-
The human Deleted in Azoospermia gene family : structure, function and evolution
… these DAZ genes encode proteins with multimeric RNAbinding domains. We found transcripts from three DAZ genes. Next we determined the molecular nature of DAZ gene polymorphism in men. We deciphered 49f/a TaqI polymorphism, which corresponds to polymorphism in 2.4 kb repeats within all DAZ genes, …
-
Co-regulation of the Smooth Muscle Cell Alternative Splicing Programme by the RNA-Binding Proteins RBPMS, RBFOX2, MBNL1, and QKI
… relationships between RBPMS and other RNAbinding proteins (RBPs) in this regulatory network remain unclear. In this study, I investigated RBFOX2, MBNL1, and QKI as potential co-regulators of RBPMS in VSMC AS regulation. RBFOX2 was identified as a key candidate due to enrichment of its …
-
High-throughput methods to analyze protein-DNA and protein-RNA interactions
… biological processes are controlled by DNA- and RNAbinding proteins. In this dissertation, I first discuss the current state of the field of transcription factor (TF) variation, and I describe in vitro and in vivo technologies for mapping TF-DNA interactions. I then describe studies that apply …
-
Characterization of split ends, a new component of the Drosophila epidermal growth factor receptor signaling pathway
… suggesting that Spen might function as an RNAbinding protein. Spen also contains a highly conserved SPOC (Spen Pearalogue and Orthologue C-terminal) domain at its C-terminus. Spen-like proteins exist from worms to humans, and they likely define a novel subfamily of RNA-binding proteins …
-
Role of PABP4 in intrauterine growth restriction
… of the poly(A)-binding protein (PABP) family of RNAbinding proteins, PABP1 and PABP4, are widely expressed in a range of adult tissues. PABP1, the prototypical family member, has been intensively characterised as central regulator of both global and mRNA-specific translation and mRNA turnover in …