Global ETD Search
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Showing 1 to 2 of 2 for “"RNAPII CTD phosphorylation"”.
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Mechanisms of recruitment of the CTD phosphatase Rtr1 to RNA polymerase II
The C-terminal domain (CTD) of the RNA polymerase II (RNAPII) subunit Rpb1 must exist in a hypophosphorylated state prior to forming a competent transcription initiation complex. However, during transcription, specific kinases and phosphatases act on the RNAPII CTD to regulate its phosphorylation …
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Investigations into the regulation of histone H2B monoubiquitination
Transkriptionsassoziierte Chromatinmodifikationen spielen eine wichtige Rolle bei der Reglation der Genexpression. So konnte die Mono-Ubiquitinierung des Lysinrestes K120 von Histon H2B (H2Bub1) beispielsweise mit transkriptionell aktiven Genen in Verbindung gebracht werden. Zum einen konnte …