Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"RNA therapy"”.
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Requirements and strategies for winning the battle against antibiotic resistance by antisense technology
… specificity of antisense molecules. For specific therapy, an antibacterial RNA must be able to distinguish between its designed targets and its off-targets. This distinction is reflected in the binding energy calculations. The major component of efficiency and specificity is uncovered to be the …
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Design, Off-Target Toxicity, and Intracellular Processing of Nucleotide-Modified Messenger RNAs for Human Therapies
RNA therapy is a modality, analogous to gene therapy, in which in vitro-transcribed mRNA (IVT mRNA) is introduced to cells for therapeutic applications. IVT mRNA is transfected into target cells, translated, and the fully-synthesised encoded protein exerts a therapeutic effect via specific …
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Pathogenic Characterization and Therapeutic Development for Fiblrolamellar Hepatocellular Carcinoma
… Then, I will discuss my work on developing an RNA-targeting therapy with antisense oligonucleotides and small interfering RNAs. I will close with a discussion on my thesis work and how I envision future research to continue from what I present here.</p>