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Showing 1 to 20 of 170 for “"RNA polymerase II"”.

  1. RNA polymerase II holoenzyme components and regulation

    Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Biology, 1999.

    mit Repository record for RNA polymerase II holoenzyme components and regulation (opens in a new tab)

  2. Yeast and mammalian RNA polymerase II holoenzymes

    Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1997.

    mit Repository record for Yeast and mammalian RNA polymerase II holoenzymes (opens in a new tab)

  3. Regulation of yeast RNA polymerase II holoenzyme transcription

    Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Biology, 1999.

    mit Repository record for Regulation of yeast RNA polymerase II holoenzyme transcription (opens in a new tab)

  4. Delineating Mechanisms of Signal-Induced RNA Polymerase II-Transcription

    … programs. Understanding the dynamics by which RNA Polymerase II precisely induces transcription to activate these programs is important for dissecting the basis for their role in cell fate responses and disease progression. Here, we utilize high-resolution genomic approaches coupled with …

    utswmed Repository record for Delineating Mechanisms of Signal-Induced RNA Polymerase II-Transcription (opens in a new tab)

  5. Regulation der RNA-Polymerase II Transkription durch humanen Mediator

    … Genen wird in Eukaryonten durch RNA-Polymerase II und die Generellen Transkriptionsfaktoren, die an den Promotor eines Klasse II Genes binden, bewerkstelligt. Eine Regulation der Aktivitaet dieser molekularen Maschine erfolgt durch Aktivator- und Repressorproteine, die …

    lmu-germany Repository record for Regulation der RNA-Polymerase II Transkription durch humanen Mediator (opens in a new tab)

  6. RNA Polymerase II control in the changing transcriptional landscape

    Eukaryotic RNA polymerase II (Pol II) is a 12 subunit complex responsible for transcribing all protein coding genes, as well as producing many other RNA species. Regulation of gene expression is essential for the viability of any organism, and it is primarily achieved at the transcriptional level. …

    cambridge Repository record for RNA Polymerase II control in the changing transcriptional landscape (opens in a new tab)

  7. Structural and biochemical characterization of RNA polymerase II transcription

    … One such mechanism involves pausing of RNA polymerase II (Pol II) in the promoter-proximal region of genes. Pausing is stabilized by the protein complexes DRB-sensitivity inducing factor (DSIF) and negative elongation factor (NELF). Prior structural and biochemical studies provide …

    mit Repository record for Structural and biochemical characterization of RNA polymerase II transcription (opens in a new tab)

  8. Sumoylation of RNA Polymerase II Regulates Transcription in Saccharomyces cerevisiae

    … reported that Rpb1, the largest subunit of RNA polymerase II (RNAPII), is sumoylated following UV-stress, our lab has shown that Rpb1 is also sumoylated under normal growth conditions. Here, we show that sumoylated Rpb1 is mostly associated with chromatin, providing further support for its …

    york Repository record for Sumoylation of RNA Polymerase II Regulates Transcription in Saccharomyces cerevisiae (opens in a new tab)

  9. Regulation of Transcription Through RNA Polymerase II Promoter-Proximal Pausing

    The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.

    utswmed Repository record for Regulation of Transcription Through RNA Polymerase II Promoter-Proximal Pausing (opens in a new tab)

  10. Molecular genetic analysis of a yeast RNA polymerase II holoenzyme

    Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1994.

    mit Repository record for Molecular genetic analysis of a yeast RNA polymerase II holoenzyme (opens in a new tab)

  11. Eukaryotic RNA Polymerase II start site detection using artificial neural networks

    … process for Eukaryotic ribonucleic acid (RNA) Polymerase II Promoter is presented in this dissertation. We employ an artificial neural network (ANN) in conjunction with features that were selected using an information-theoretic approach. Firstly an introduction is given where the problem …

    pretoria Repository record for Eukaryotic RNA Polymerase II start site detection using artificial neural networks (opens in a new tab)

  12. Functional antagonism of the RNA polymerase II holoenzyme by negative regulators

    Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1997.

    mit Repository record for Functional antagonism of the RNA polymerase II holoenzyme by negative regulators (opens in a new tab)

  13. Regulation Of Transcription By RNA Polymerase II In <i>S. pombe</i>

    … thesis research focusses on an analysis of the RNA Polymerase II elongation factor Ell1/Eaf1 in <i>S. pombe</i>. Eleven-nineteen lysine-rich in leukemia (ELL) is encoded by a gene involved in translocations with MLL in leukemia and forms a tight complex with ELL-associated factors (EAF). ELL/EAF …

    the-open-u Repository record for Regulation Of Transcription By RNA Polymerase II In <i>S. pombe</i> (opens in a new tab)

  14. An Alternative View of the Templates and Functions of RNA Polymerase II

    <p>RNA polymerase II (pol II) has been implicated in the RNA-templated RNA synthesis during replication of some Viroids and Hepatitis Delta Virus (HDV). In this study HDV RNA-templated pol II transcription was examined in vitro, using HeLa cell nuclear extracts (NE). Under standard conditions for …

    rockefeller Repository record for An Alternative View of the Templates and Functions of RNA Polymerase II (opens in a new tab)

  15. Mechanisms of recruitment of the CTD phosphatase Rtr1 to RNA polymerase II

    The C-terminal domain (CTD) of the RNA polymerase II (RNAPII) subunit Rpb1 must exist in a hypophosphorylated state prior to forming a competent transcription initiation complex. However, during transcription, specific kinases and phosphatases act on the RNAPII CTD to regulate its phosphorylation …

    iupui Repository record for Mechanisms of recruitment of the CTD phosphatase Rtr1 to RNA polymerase II (opens in a new tab)

  16. Functional divergence of the RNA polymerase II transcription machinery in Plasmodium falciparum

    … orthologue of general transcription factor IIB (TFIIB). Through the biochemical characterisation of protein-DNA interactions, protein-protein interactions and the biomolecular condensation properties of these transcription factors, this study aimed to provide insight into the molecular …

    cape-town Repository record for Functional divergence of the RNA polymerase II transcription machinery in Plasmodium falciparum (opens in a new tab)

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