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Showing 1 to 4 of 4 for “"RNA exosome complex"”.
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Genetic Analysis of Rna Exosome Complex Cofactors
<p>The RNA exosome complex is known to process and/or degrade many classes of RNA, including mRNA, rRNA, tRNA and snRNA, through its 3’-to-5’ exoribonuclease catalytic activity. The RNA exosome complex comprises a 9-unit core (exo-9), with six proteins making up a PH-Ring barrel and three proteins …
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Functional Consequences of Rna Exosome Complex Alteration By Conformational Changes and Cofactor Binding
<p>The RNA exosome is an essential 3’-5 ribonuclease that processes or degrades a variety of RNA species in eukaryotes. It is composed of nine structural cores and one catalytic subunit, Rrp44. Structural studies captured two different conformations of Rrp44, Rrp44<sup>ch</sup> (channel) and …
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Post Translational Regulation of AID Targeting to Both Strands of a Transcribed DNA Substrate
… such as R loops, transcription factors, miRNA, and phosphorylation as events important for determining AID's ability to access its substrate sequences. However, none of these studies demonstrated how AID mutates both strands of DNA, reminiscent to its in vivo mode of action.The focus of …
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Functions of RNA exosome and tRNA splicing ligase in Mendelian and Infectious diseases
<p>Functions of RNA exosome and tRNA splicing ligase in Mendelian and Infectious diseases</p> <p>Khondakar Sayef Ahammed, M.S.</p> <p>Advisory Professor: Ambro van Hoof, Ph.D.</p> <p><strong> </strong></p> <p>RNA maturation and degradation reactions are important for health and survival of all …