Global ETD Search
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Showing 1 to 2 of 2 for “"RNA disruption"”.
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Cellular mechanisms associated with chemotherapy induced ribosomal RNA disruption in ovarian cancer cells
The degradation of RNA is a ubiquitous process prevalent in all cells; employed to maintain nucleotide turnover, maturation, and quality control of RNA. A recent breast cancer clinical trial demonstrated that the degradation of ribosomal RNA (rRNA) in tumour biopsies, referred to as RNA disruption, …
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Stress-induced transcription factors and their role in RNA disruption in ovarian cancer cells
… chemotherapy treatment, their tumour ribosomal RNA (rRNA) is degraded, which has been termed RNA Disruption. The RNA disruption assay (RDA) has been developed to quantify RNA disruption as an RNA disruption index (RDI), which is the mass ratio of degraded to intact rRNAs. The underlying …