Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"RNA amplification"”.
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Gene expression microarray analysis of small, purified cell subsets
… examining all of the cellular processes at the mRNA level at a given moment. One major challenge in its applicability is that most biological samples are cell mixtures and the cell type of interest is often a minor cell subset. Using well-defined mixtures of model cell types with different cell …
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Signal Processing Techniques Applied to Biomedical Diagnostics
… with isothermal CRISPR-Cas12a-based DNA/RNA amplification to detect clinically relevant targets with high specificity. Finally, we evaluate the clinical performance of our systems in detecting target genes for (1) SARS-CoV-2, the virus responsible for the COVID-19 pandemic, and (2) Human …
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Ultrasensitive quantification of circulating disease biomarkers through enzymatic labeling and single molecule counting
… improved methods for the quantification of microRNA (miRNA) and protein in biological fluids. The first of my projects relates to the ultrasensitive detection of miRNA, one of the most exciting emerging classes of biomarkers. In recent years, miRNA in blood circulating have been identified as …
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DEVELOPMENT OF E-SRS (ENVIRONMENT-SENSING RESPONSE SYSTEM) AS A NOVEL METHOD TO DISTINGUISH GENETIC ENVIRONMENTS AND RESOLVE CLOSELY RELATED NUCLEIC ACID SEQUENCES
… and response system with two components: 1) An RNA based sensor that changes conformation and activates upon binding specific NTS; 2) A Response System that is triggered by the activated sensor to initiate some physical response, such as emitting a fluorescent signal to indicate presence of the …