Global ETD Search
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Showing 1 to 5 of 5 for “"RNA Polymerase III transcription"”.
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In vivo studies of repressors of RNA polymerase III transcription
RNA polymerase III (Pol III) is responsible for transcribing a relatively small but vital set of genes, including 5S rRNA and tRNAs. Pol III transcription has been shown to be upregulated in transformed and cancer cells, suggesting an important role in cell growth and proliferation. Its tight …
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Extra-Transcriptional Effects of Chromatin Bound RNA Polymerase III Transcription Complexes
Transcription by RNA polymerase III (Pol III) requires sequential assembly of Pol III-specific transcription factors. At the tRNA gene, the TFIIIC complex recognizes and specifically binds at intragenic promoter elements A-box and B-box and aids the assembly of TFIIIB to upstream of the …
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The regulation of RNA polymerase III transcription by protein kinase CK2
… depends primarily on the rate of translation. RNA polymerase (pol) III plays a key role in protein synthesis by catalysing the production of small, untranslated RNA molecules such as transfer (tRNA) and 5S ribosomal RNA (5S rRNA). Indeed, recent evidence suggests that tRNAiMet production is …
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Regulation of RNA polymerase III transcription by the ID1, ID2, ID3 and E47 proteins
RNA polymerase III (pol III) is responsible for transcribing a set of genes that are involved in protein synthesis, including transfer (tRNA) and 5S ribosomal RNA (5S rRNA). Pol III transcription levels are increased in many cancers, as increased protein synthesis is required for tumour growth. …
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Dissecting the regulatory roles and cellular functions of mammalian ZSCAN5B and primate-specific paralogs
"Certain subfamilies of zinc finger transcription factors (ZNF-TFs), especially those including KRAB or SCAN protein-interaction domains, have evolved rapidly in mammals due to repeated rounds of gene duplication, deletion, and divergence. The functions of the encoded proteins, and the evolutionary …