Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"RNA Motif"”.
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Locomotif - a graphical programming system for RNA motif search
… and installing a software environment for RNA motif searches: Locomotif. It includes a visual editor for motif definition, translation of the motif structure to XML code and client-server interactions, and further, translation of the XML code to ADP and compilation to C.
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The Role of G-Quadruplex RNA Motif in Fragile X Syndrome
… X mental retardation protein (FMRP). As an RNA binding protein, FMRP has been proposed to regulate the transport and translation of specific message RNA (mRNA). It has been reported that FMRP uses its RGG box domain to bind mRNA targets that form a G-quadruplex structure, structure believed …
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Design and implementation of a cyberinfrastructure for RNA motif search, prediction and analysis
RNA secondary and tertiary structure motifs play important roles in cells. However, very few web servers are available for RNA motif search and prediction. In this dissertation, a cyberinfrastructure, named RNAcyber, capable of performing RNA motif search and prediction, is proposed, designed and …
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Data mining of tetraloop-tetraloop receptors in RNA XML files
RNA (Ribonucleic acid) Motifs are tertiary structures that play an important role in the folding mechanism of the RNA molecule. The overall function of a RNA Motif depends on its specific bp (base pairs) sequence that constitutes the secondary structure. Data mining is a novel method in both …
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Aminormotiffinder - a graph grammar based tool to effectively search a minor motifs in 3D RNA molecules
RNA Motifs are three dimensional folds that play important role in RNA folding and its interaction with other molecules. They basically have modular structure and are composed of conserved building blocks dependent upon the sequence. Their automated in silico identification remains a challenging …
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A data science approach to pattern discovery in complex structures with applications in bioinformatics
… science approach for discovering patterns or motifs from complex structures, particularly complex RNA structures. RNA secondary and tertiary structure motifs are very important in biological molecules, which play multiple vital roles in cells. A lot of work has been done on RNA motif …
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Multiple regulatory layers in the establishment of Rbfox2 splicing networks
Regulated alternative splicing is mediated by RNA binding proteins (RBPs) recognizing short sequence motifs in nascent transcripts. The Rbfox RBPs are highly conserved splicing factors that regulate tissue-specific exon inclusion by binding the RNA motif UGCAUG. We sought to comprehensively define …
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RNA structure analysis : algorithms and applications
… thesis, efficient algorithms for aligning RNA secondary structures and mining unknown RNA motifs are presented. As the major contribution, a structure alignment algorithm, which combines both primary and secondary structure information, can find the optimal alignment between two given …
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Regulating transcript fate through RNA elements in the 3' untranslated region
… on the post-transcriptional regulation of mRNAs via miRNAs, other small RNAs, and RNA binding proteins. Controlled translation of transcripts has been shown to play a vital role in rapid response to changing conditions such as dendritic tree formation, ischemia, heat shock, and immune …
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Struktur-Funktionsbeziehungen und Inhibition retroviraler Reverser Transkriptasen
… Polymerase- und eine C-terminale Ribonuklease H (RNase H)-Domäne. Die Polymerasedomäne kann in die Handflächen-, Finger-, Daumen- und Verbindungssubdomäne unterteilt werden. Letztere verbindet die Polymerasedomäne mit der C-terminalen RNase H. Während der Reversen Transkription schreibt die RT die …
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Foamy Virus RNase H - Aktivität, Struktur und Funktion
Zusammenfassung Das für die Replikation des RNA-Genoms von Foamy Viren (FV) notwendige Enzym, die Protease-Reverse Transkriptase (PR-RT), beinhaltet die Protease-, die Polymerase- und RNase H-Domäne. Letztere ist für den Abbau der RNA im entstehenden RNA/DNA Hybrid verantwortlich. Während die FV …