Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"RIT1"”.
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Oncogene-driven post-transcriptional regulation in lung cancer
… tumors. A gene of the same family, RIT1, is mutated or amplified in 10-15% of lung adenocarcinomas. Although therapies targeting some KRAS-mutated tumors have begun to enter the clinic, a comprehensive understanding of the Ras family and their regulatory functions continues to elude …
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Genetic investigation of South Africans with the Noonan Syndrome phenotype using targeted next generation sequencing
… HRAS, KRAS, MAP2K1, MAP2K2, NRAS, PTPN11, RAF1, RIT1, SHOC2, SOS1 and SPRED1. Results: Of the 26 patients included, 50% had a family history suggestive of NS. The median age at diagnosis was4.5 years (range: 1month-51years). Individuals of mixed-race ancestry were most represented (53.8%), …