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Showing 1 to 8 of 8 for “"RISK pathway"”.

  1. Isoflurane-induced post-conditioning in senescent hearts is attenuated by failure to activate reperfusion injury salvage kinase pathway

    … of the reperfusion injury salvage kinase (RISK) pathway to address a possible mechanism underlying age-related differences. METHODS AND RESULTS: Male Wistar rats were assigned to age groups (young, 3–5 months; old, 20–24 months), and randomly selected to receive isoflurane (1 minimum …

    ajou Repository record for Isoflurane-induced post-conditioning in senescent hearts is attenuated by failure to activate reperfusion injury salvage kinase pathway (opens in a new tab)

  2. The Moderating Effects of Parenting on the Development of Externalizing Problems in Toddlers

    … children were 2, 3, and 4 years. An incremental risk model was hypothesized to explain the emergence of externalizing behavior problems. Theoretically, children's temperamental propensity towards negative emotional reactivity increases risk for noncompliance, noncompliance that increases risk for …

    uno Repository record for The Moderating Effects of Parenting on the Development of Externalizing Problems in Toddlers (opens in a new tab)

  3. Locus of Control and Depression as Mechanisms in the Relationship between Racial Discrimination and Substance Use

    … discrimination has been consistently linked with risk for substance use. However, outside of affect-based factors, few other mechanisms have been examined in the literature. One potential candidate is locus of control (LOC). LOC is a learning processes that involves the degree to which an …

    iupui Repository record for Locus of Control and Depression as Mechanisms in the Relationship between Racial Discrimination and Substance Use (opens in a new tab)

  4. Coping Motives as a Mediator of the Relationship between Trauma Exposure and Substance Misuse in South African Adolescents

    … and communities, which places them at a greater risk of developing substance misuse. Studies in high-income countries have shown that substance misuse in traumatised adults is driven by their ‘coping motives': maladaptive beliefs that substances help cope with negative affect. However, very few …

    cape-town Repository record for Coping Motives as a Mediator of the Relationship between Trauma Exposure and Substance Misuse in South African Adolescents (opens in a new tab)

  5. An improved directed random walk framework for cancer classification using gene expression data

    … improved DRW framework is proposed to identify risk pathway while correctly predict the significant genes. It is named as significant directed walk (SDW) because of its ability to identify significant genes for cancer. In this study, six gene expression datasets are applied to study the …

    uthm Repository record for An improved directed random walk framework for cancer classification using gene expression data (opens in a new tab)

  6. Determining the role of the LPI/GPR55 system in the development of obesity and associated cardiovascular consequences.

    … due to HFD intervention was not dependent on RISK-pathway activation and was not observed in hearts from GPR55-/- mice, therefore demonstrating that the cardio-protective effect of a HFD on infarct size is dependent on GPR55. In vitro studies using 3T3-L1 cells determined that the changes in …

    rgu Repository record for Determining the role of the LPI/GPR55 system in the development of obesity and associated cardiovascular consequences. (opens in a new tab)

  7. Whole genome sequencing approach to identifying genetic risk factors underlying anterior cruciate ligament injuries in a twin family study

    … a complex interplay of intrinsic and extrinsic risk factors. Variation in the genome is now considered a key intrinsic risk factor, but the majority of currently implicated loci have been identified through case-control genetic association studies, which are limited by a candidate gene approach …

    cape-town Repository record for Whole genome sequencing approach to identifying genetic risk factors underlying anterior cruciate ligament injuries in a twin family study (opens in a new tab)