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Showing 1 to 6 of 6 for “"RINm5F"”.

  1. Pancreatic peptide hormone expression in the RINm5F cell line

    Van der Merwe, Elizabeth LaelDivision of Cell Biology1994

    … in vitro. In the present study, the RINm5F cell line (Oie ~-, 1983) was investigated to determine whether or not it would be suitable for this purpose. This study presents the results from work aimed at determining which hormone-producing phenotypes were expressed under routine and …

    cape-town Repository record

  2. Differentielle Genexpression in der Insulinoma-Zelllinie RINm5F nach Stimulation mit Leptin

    Hekerman, PaulPublikationsserver der RWTH Aachen University2004

    … genes. I have used the pancreatic beta cell line RINm5F, which I transfected stably with the leptin receptor (LepRb) cDNA using a retroviral expression system. These cells were stimulated with leptin, IL-6 or GH, and STAT factor phosphorylation was analysed. Leptin stimulated tyrosine …

    aachen Repository record

  3. Sustained enhancement of Ca[2+] influx by glibenclamide induces apoptosis in RINm5F cells

    Iwakura, ToshioKyoto University2001

    kyoto Repository record

  4. The impact of oxidative stress and potential antioxidant therapy on function and survival of cultured pancreatic β-islet cells

    Kanase, NileshUniversity of Edinburgh2011

    … of oxidative stress in pancreatic -islet RINm5F cells, at least in H2O2 model. The results point to an indirect method of protection, and one that favours protection against mitochondrial dysfunction over loss of membrane integrity. None of the curcuminoids showed a detrimental effect on …

    uhi-uk Repository record

  5. Regulation der Genexpression und Promotoraktivität von RGS4 durch Leptin

    Korfmacher, StefaniePublikationsserver der RWTH Aachen University2008

    … analysis using phosphospecific antibodies in rat RINm5F insulinoma cells, it was shown that leptin is able to activate both transcription factor STAT1 and STAT3. In contrast, IFN-g specifically activates STAT1 while IL-6 activates only STAT3. Subsequently, the role of STAT1 and STAT3 in the …

    aachen Repository record

  6. Role of Transient Receptor Potential (TRP) Channels in Nociception

    Cao, Deshou2009

    … decreased insulin release. TRPV4 is expressed in RINm5F (beta cell line), islets and pancreas. It has been shown that hypotonicity induced insulin release in beta cell lines, which was mediated by activation of stretch-activated channels, raising the possibility of the involvement of TRPV4, a …

    siu-theses Repository record