Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 47 for “"RHD"”.
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The household economic impact of Rheumatic Heart Disease (RHD) in South Africa
Background: Rheumatic heart disease (RHD) remains a major public health concern in African countries due to the high rates of complications such as atrial fibrillation, stroke, infective endocarditis, and heart failure, all of which can result in premature death. In 2015, RHD was estimated to …
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The Economic Impact of Rheumatic Heart Disease (RHD) on the Health System of South Africa. A Cost of Illness Study.
Background Rheumatic Heart Disease (RHD) is a disease of poverty that is neglected in developing countries. The consequences of RHD are increasingly becoming huge economic burden to the health system and consecutively the government. Despite RHD being preventable, most of the RHD related deaths …
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Outcomes of asymptomatic and symptomatic rheumatic heart disease
Rheumatic Heart Disease (RHD) is a leading cause of heart disease in children and young adults in the developing world, with significant associated morbidity and mortality. Early secondary prophylaxis may retard the deleterious progression from its antecedent, acute rheumatic fever to permanent …
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Prevalence, and outcomes of Rheumatic Heart Disease in Ethiopia: a systematic review and meta-analysis
… as having one of the highest burdens of RHD with a prevalence of 100-149 persons per 100,000 population. We therefore sought to estimate the prevalence of RHD, and clinical and post-operative outcomes, in Ethiopia. Objectives: We conducted a systematic review of the prevalence and …
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A study of determinants and prevalence of Rheumatic Heart Disease in Cape Town
Rheumatic Heart Disease (RHD) is a post-infectious immune disease ascribed to an interaction between a rheumatogenic strain of group A streptococcus, a susceptible host who lives in poor social conditions with limited access to medical facilities. The disease process begins with repeated group A …
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Investigation of circulatory and tissue-specific metabolomic biomarkers in valvular heart disease using mass spectrometry
… in patients with rheumatic heart disease (RHD) and degenerative aortic stenosis (AS), compared to matched, healthy controls. The study hypothesis was that cardiac tissue obtained from heart valve biopsies from RHD and degenerative AS patients would have distinct histological features. The …
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Characterisation of phenotypes of inflammation, fibrosis and remodeling in chronic rheumatic heart disease using multiparametric cardiovascular magnetic resonance and autophagy markers
Background: Rheumatic heart disease (RHD), concomitant to valvular damage, heart failure, arrhythmias and pulmonary hypertension is the major source of cardiovascular morbidity and mortality in the young, predominantly in low- and middle-income countries (LMICs). We investigated the association of …
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Biochemistry: Production of recombinant Rh blood group antigens for detection of alloimmunisation
… containing di erent external loops of the human RhD protein. Human RhD external loop 6 was the most suitable candidate to start with due to its location between highly conserved domains of the protein. The hybrid gene for the NeRH50"human RHD was sub-cloned into an expression vector (pET) and …
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Biomarkers for autoimmunie disease diagnosis in the public health sector: A systematic review and meta-analysis
Rheumatic heart disease (RHD), rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are autoimmune diseases with drastic effects on quality of life. Diagnostic challenges remain, especially given the prevalence of these diseases among people of low socioeconomic status. The purpose of …
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Integrating the prevention and control of rheumatic heart disease into country health systems: a systemic review
… be used when analysing rheumatic heart disease (RHD) prevention and care programmes. Part B is a literature review which expands on the protocol. An in-depth explanation of the disease process is presented in order to understand the multiple opportunities for preventing RHD and its precursors. …
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Carer Information Needs Following a Family Member's Right Hemisphere Stroke
… needs of carers with right hemisphere disorder (RHD). RHD describes cognitive and communication impairments a person experiences following a right hemisphere stroke or brain injury. Carers have an important role in rehabilitation and the long-term quality of life of a person with RHD. This study …
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Standard echocardiography versus handheld echocardiography for the detection of subclinical rheumatic heart disease: A systematic review
Rheumatic heart disease (RHD) is a permanent heart valve condition resulting from an abnormal immune reaction to group A streptococcal (GAS) infection typically occurring in childhood. If left untreated, disease progression can result in irreversible heart valve damage, cardiac failure, stroke and …
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Accelerating Astrophysical Simulations with GPUs: A Case Study of Radiative Transfer in arepo-rt
… integration into radiation-hydrodynamics (RHD) simulations is computationally demanding, particularly due to the stringent time-stepping conditions and increased dimensionality inherent in multifrequency collisionless Boltzmann physics. The recent emergence of exascale supercomputers, …
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Cell-free fetal DNA (cffDNA) enrichment for non-invasive prenatal testing (NIPT): a comparison of molecular techniques
… PCR (qPCR) was compared for fetal sex and RHD genotyping. In addition RHD zygosity testing was carried out for non-maternal samples. Consequently, Pippin Prep™ gel electrophoresis was combined with ddPCR analysis for the NIPD of Down Syndrome (DS) in pseudo-maternal samples. The results …
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A tri-phasic continuum model for the numerical analysis of biological tissue proliferation using the Theory of Porous Media. Application to cardiac remodelling in rheumatic heart disease
… Attention is given to Rheumatic Heart Disease (RHD) - a valvular heart disease. RHD is a condition which is mostly common amongst poorer regions and mainly affects young people, of which claims approximately 250 000 lives per annum. The Theory of Porous Media (TPM) can represent the …
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Acquired brain injury and the unraveling of theory of mind: exploring the role of personality change and spatial cognition
… (ToM) following right hemisphere dysfunction (RHD) due to Acquired Brain Injury (ABI). Given the critical role of the right hemisphere in social and emotional behavior, this research focuses on understanding the connection between ToM and personality alterations, particularly as they relate to …
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The effect of distance to health facility on the maintenance of INR therapeutic ranges in rheumatic heart disease patients from Cape Town
… registry for rheumatic heart disease (RHD). This study made use of geographical information systems (GIS) as a tool to investigate the effect of distance on the maintenance of INR therapeutic ranges in RHD patients. Part B: elaborates on the background and highlights the importance of …
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Numerical simulations of mass outflows from star-forming regions
… moment equations is developed and tested for RHD simulations. The moment equations are closed with the tensor variable Eddington factor whose components are computed from angular quadratures of the specific intensity which, in turn, is computed from a formal solution of the two dimensional …
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