Global ETD Search
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Showing 1 to 4 of 4 for “"RHAMM"”.
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RHAMM Alters Vascular Smooth Muscle Cell Constrictive Matrix Remodeling
… the receptor for hyaluronan-mediated motility (RHAMM), affects arterial SMC adhesion, migration and collagen matrix remodeling in vitro as well as constrictive remodeling following artery injury in vivo.
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The Effects of RHAMM on Cell Division, Cell Motility, and Tumorigenesis
Overexpression of a RHAMM isoform (RHAMMΔ163) transforms fibroblasts but the mechanisms underlying this oncogenic function are not well understood. RHAMMΔ163 binds to the mitotic spindle and centrosomes via a C-terminal leucine zipper; these interactions are predicted to regulate genomic stability …
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Design and Synthesis of Hyaluronan:RHAMM Interaction Inhibitors
… The receptor for hyaluronan-mediated motility (RHAMM) binds to HA and has limited constitutive expression but is upregulated during tissue injury. Blocking HA fragment:RHAMM interactions has therapeutic potential for treating cancer but truncation of RHAMM into peptides mimicking only the HA …