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Showing 1 to 4 of 4 for “"RHAMM"”.

  1. RHAMM Alters Vascular Smooth Muscle Cell Constrictive Matrix Remodeling

    … the receptor for hyaluronan-mediated motility (RHAMM), affects arterial SMC adhesion, migration and collagen matrix remodeling in vitro as well as constrictive remodeling following artery injury in vivo.

    wfu Repository record for RHAMM Alters Vascular Smooth Muscle Cell Constrictive Matrix Remodeling (opens in a new tab)

  2. The Effects of RHAMM on Cell Division, Cell Motility, and Tumorigenesis

    Overexpression of a RHAMM isoform (RHAMMΔ163) transforms fibroblasts but the mechanisms underlying this oncogenic function are not well understood. RHAMMΔ163 binds to the mitotic spindle and centrosomes via a C-terminal leucine zipper; these interactions are predicted to regulate genomic stability …

    uwo Repository record for The Effects of RHAMM on Cell Division, Cell Motility, and Tumorigenesis (opens in a new tab)

  3. Design and Synthesis of Hyaluronan:RHAMM Interaction Inhibitors

    … The receptor for hyaluronan-mediated motility (RHAMM) binds to HA and has limited constitutive expression but is upregulated during tissue injury. Blocking HA fragment:RHAMM interactions has therapeutic potential for treating cancer but truncation of RHAMM into peptides mimicking only the HA …

    uwo Repository record for Design and Synthesis of Hyaluronan:RHAMM Interaction Inhibitors (opens in a new tab)