Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"RHAMM"”.
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RHAMM Alters Vascular Smooth Muscle Cell Constrictive Matrix Remodeling
… the receptor for hyaluronan-mediated motility (RHAMM), affects arterial SMC adhesion, migration and collagen matrix remodeling in vitro as well as constrictive remodeling following artery injury in vivo.
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The Effects of RHAMM on Cell Division, Cell Motility, and Tumorigenesis
Overexpression of a RHAMM isoform (RHAMMΔ163) transforms fibroblasts but the mechanisms underlying this oncogenic function are not well understood. RHAMMΔ163 binds to the mitotic spindle and centrosomes via a C-terminal leucine zipper; these interactions are predicted to regulate genomic stability …
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Design and Synthesis of Hyaluronan:RHAMM Interaction Inhibitors
… The receptor for hyaluronan-mediated motility (RHAMM) binds to HA and has limited constitutive expression but is upregulated during tissue injury. Blocking HA fragment:RHAMM interactions has therapeutic potential for treating cancer but truncation of RHAMM into peptides mimicking only the HA …
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In vivo responses of neural progenitor cells to extracellular matrix signaling under pathological conditions
… In paper III, we were interested in the role of RHAMM, the receptor for hyaluronan, one of the most abundantly expressed glycosaminoglycans in the brain extracellular matrix, in stroke-induced neurogenesis. We observed RHAMM in both unlesioned and unlesioned animals being important for cell …