Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 133 for “"RESPIRATORY DISTRESS"”.
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Respiratory distress in newborn infants
… may be more commonly associated with failure of respiratory adaptation than with any other adaptational failure" (Smith, 1964). About two-thirds of all deaths in the newborn are associated with respiratory failure (Briggs and Nogg, 1958; Drissell and Smith, 1962). Hutchisen et al (1962) stated …
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Endotype Discovery in Acute Respiratory Distress Syndrome
Endotype Discovery in Acute Respiratory Distress Syndrome Dr Romit Samanta Acute respiratory distress syndrome (ARDS) affects 10% of critical care patients and is characterised by acute refractory hypoxaemia and bilateral pulmonary infiltrates on thoracic imaging. Mortality from severe ARDS is …
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The Respiratory Distress Observation Scale (RDOS), Pain, and Agitation
The Respiratory Distress Observation Scale (RDOS) is relatively new and has not been extensively evaluated. The purpose of this study was to, a) explore the incidence and severity of respiratory distress in the cognitively impaired adult patient on mechanical ventilation, b) examine the …
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Biochemical aspects of the idiopathic respiratory distress syndrome of the newborn
This study was undertaken primarily to investigate the plasma protein system in infants with IRDS, as compared with healthy premature infants, as it had previously been reported that the plasma protein concentration in affected infants was abnormally low. It was attempted further to establish …
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Respiratory Distress Education: Effect on Nurses' Knowledge and Intent to Change Practice
… educational presentation on nurses’ knowledge of respiratory distress and the intent to change their practice when caring for patients on a step-down unit at Tucson Medical Center. Background: Hospitalized patients have been increasing in acuity and nurses are caring for extremely ill patients. …
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Identification of novel coding single nucleotide polymorphisms associated with acute respiratory distress syndrome
… in complex genetic conditions such as acute respiratory distress syndrome (ARDS). To identify disease-causing variants in ARDS patients, whole-exome sequencing was performed on 96 patient DNA samples from the National Heart, Lung and Blood Institute's ARDS Network (ARDSnet). By comparing …
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The effects of mechanical ventilation on the development of Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome (ARDS) is a severe lung illness characterized by inflammation and fluid accumulation in the respiratory system. Historically, ARDS and other forms of respiratory failure have been treated using mechanical ventilation to help maintain gas exchange in the lungs. …
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The role of inflammasomes in a murine model of acute respiratory distress syndrome (ARDS)
Acute respiratory distress syndrome is rapid pulmonary inflammation that can cause organ failure which is commonly caused by sepsis, severe pneumonia and trauma. ARDS has become one of the top research priorities since the SARS-CoV-2 outbreak in 2020. From injury to damaged tissue repair, cell …
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Human mesenchymal stromal cell regulation of pulmonary macrophage populations in the Acute Respiratory Distress Syndrome
The Acute Respiratory Distress Syndrome (ARDS) is a devastating clinical disorder characterised by excessive inflammation in the alveolar compartment resulting in oedema of the airspaces due to loss of integrity in the alveolar epithelial-endothelial barrier. ARDS is associated with high mortality …
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Incidence and Pathogenesis of Acute Lung Injury and the Acute Respiratory Distress Syndrome in Humans
… injury (ALI) and it’s more severe form, acute respiratory distress syndrome (ARDS), are conditions characterised by neutrophilic pulmonary inflammation, refractory hypoxaemia and diffuse alveolar damage. This work reports on the first UK based prospective study of the incidence and longer term …
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Exogenous surfactant transport through the pulmonary airways : improving surfactant replacement therapy for neonatal respiratory distress syndrome
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1996.
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OPTIMIZATION OF AAV9 GENE THERAPY FOR SPINAL MUSCULAR ATROPHY WITH RESPIRATORY DISTRESS TYPE 1 USING IN VIVO DISEASE MODELS
Spinal Muscular Atrophy with Respiratory Distress type 1 (SMARD1) is a rare autosomal recessive motoneuron disease with infantile onset, with an estimated incidence of 1/100’000. It is caused by mutations in the immunoglobulin mu-binding protein 2 (IGHMBP2) gene, which lead to a deficient amount of …
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Diagnostic utility of lung ultrasound in preterm neonates with respiratory distress at a tertiary neonatal intensive care unit in the Western Cape
… in preterm babies receiving non-invasive respiratory support in a South African neonatal unit, and to compare LUS with clinical diagnoses and surfactant administration. Methods: We conducted a prospective, observational study of babies 27–34 weeks' gestation, birth weight ≥ 800 grams, …
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A new blood pump and oxygenator system for support of infants with neonatal respiratory distress: preliminary in vitro and in vivo evaluation
… pumping system for the support of neonates with respiratory deficiencies. Such systems now available for support of adults are not suitable for neonatal patients. In vitro evaluation of a new blood oxygenator and blood pumping system was performed. The data obtained suggested that this system may …
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Relating Heart Rate Variability, Urinary Catecholamines, and Baseline Fitness to Respiratory Distress Index and Severity of Disease in Obstructive Sleep Apnea Patients
… exists between severity of OSA as assessed by respiratory distress index (RDI) and the selected measures HRV, fitness, QOL, and catecholamine output. Subjects were 6 men and 5 women who were recently diagnosed with OSA by polysomnographic (PSG) study. HRV and blood pressure was measured during …
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Effects of hypercapnic acidosis on the primary cells relevant to acute respiratory distress syndrome pathophysiology and the therapeutic potential of Mesenchymal Stem Cells
Acute Respiratory Distress Syndrome (ARDS) is an inflammatory disorder in which the integrity of the alveolar epithelial-capillary endothelial barrier breaks down, facilitating the accumulation of a protein-rich oedema fluid within the alveoli. Despite years of clinical trials, no effective …
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Outcomes of patients with COVID-19 Acute Respiratory Distress Syndrome requiring Invasive Mechanical Ventilation admitted to an Intensive Care Unit in South Africa
Background Up to 30% of patients with COVID-19 pneumonia may require ICU admission or mechanical ventilation [Guan et al., 2020; Huang et al., 2020]. Data from low- and middle-income countries for COVID-19 ARDS are limited. Groote Schuur Hospital in Cape Town, South Africa expanded its ICU service …
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The respiratory distress syndrome of the newborn : studies of blood gases and acid/base balance with the object of formulating principles of treatment
Respiratory failure accounts for a large, if not the largest, percentage of deaths during the first 48 hours of life. During the last ten years a great deal of research has been devoted to this early respiratory failure. The syndrome has been known by different names at different times; hyaline …
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