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Showing 1 to 2 of 2 for “"REEP5"”.
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REEP5-MFN1/2 tethering in ER-mitochondria crosstalk
… formation and function. Our study identified REEP5, a member of the ER membrane-shaping protein family, as a key mediator of ER-mitochondria tethering through a targeted screen and demonstrated its specific interaction with mitochondria-localized MFN1/2 at MERCs. The interaction involves the …
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Identification and Characterization of the Role of REEP5 in Sarco-Endoplasmic Reticulum Formation, Maintenance, and Function in Cardiac Muscle
… and cardiac-enriched membrane proteins was REEP5, a sarco-endoplasmic reticulum (SR/ER) membrane protein. In a follow-up study we tested the hypothesis that physiological REEP5 expression is important for cardiac SR/ER organization and heart function. In vitro REEP5 depletion in isolated …