Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"RCAS"”.
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Identification and Characterization of Genes Associated with <i>V-Jun</i> Induced Cell Transformation
… normal CEF infected with vector sequences only (RCAS).</p> <p>Another is clone 15-15, showing strong sequence identity to the chicken Apolipoprotein A1 (ApoA1) gene. Northern blot analysis demonstrates that the steady state levels of ApoA1 mRNA in RCAS is 3 to 10 times higher than in VJ-1 cells, …
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A linear parameter varying control methodology for reduction of helicopter higher harmonic vibration
… in the Rotorcraft Comprehensive Analysis System (RCAS) aeromechanical simulation environment indicates that the steady state vibration levels and the helicopter dynamics depend primarily on the advance ratio. Two baseline vibration controllers are developed, specifically the Continuous Time Higher …
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Children's Religious Coping Following Residential Fires: An Exploratory Study
… of the Religious Coping Activities Scale (RCAS; Pargament et al., 1990) in children and adolescents and explored its utility in predicting children's religious coping over time: moreover, the study evaluated its role in predicting PTSD symptomatology over an extended period of time. This …
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Three Essays on the East Asian Miracle of Thailand
… index (RCA) introduced by Balassa in 1965, RCAs of manufacturing indicate that mostly labor-intensive manufactured products have dominated the manufactured exports of Thailand. Although there was a tendency that the pattern of comparative advantage would shift towards technology-intensive …
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Study of recycled concrete aggregate as filter media for phosphorus removal in synthetic wastewater
… as the percentage of phosphorus removal using RCAs of two different sizes namely, 5 mm to 10 mm and 25 mm to 30 mm. A total of five vertical laboratory-scale RCA filters were designed and five different concentrations of synthetic wastewater between 10 – 50 mg/L were prepared. The samples taken …
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Tumor-assoziierte Mikroglia und Makrophagen modellieren durch GPNMB das Tumorwachstum und die Immunzellinfiltration in malignen Gliomen
… in human glioblastoma multiforme and the murine RCAS-PDGFb high grade glioma model. Loss of GPNMB in the in vivo tumor microenvironment results in significantly smaller tumor volumes and generates a pro-inflammatory innate and adaptive immune cell microenvironment. The impact of host-derived …
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Exploring the immunologic consequences of ATRX deficiency in glioma
… gliomas with both CRISPR knock-out and the Tva-RCAS system, as well as generating a single-cell RNA sequencing data set from the CD45-sorted immune component of human ATRX-deficient Astrocytoma and ATRX-intact Oligodendroglioma. In our murine models, we observed that ATRX-deficient tumors …
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Elucidating The Igfbp2 Signaling Pathway In Glioma Development and Progression
… its ability to induce glioma progression in the RCAS/tv-a spontaneous glioma mouse model. We found that ILK is a key downstream mediator of IGFBP2 that is required for the induction of glioma progression. Most significantly, a genetic therapeutic approach revealed that perturbation of any point …
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OXIDATIVE PHOSPHORYLATION IN MELANOMA BRAIN METASTASES: A REGULATOR of THE TUMOR IMMUNE LANDSCAPE
… of mitochondrial complex I. PGC1a KO in an RCAS-TVA mouse model of autochthonous lung and brain tumors developing from primary melanomas significantly reduced the incidence of lung and brain tumor formation. Further characterization of OXPHOS at later stages of metastasis (circulation and …
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Oxidative Phosphorylation: A Critical Feature and Novel Therapeutic Target In Melanoma Brain Metastases
… I clinical trials. IACS-010759 treatment of an RCAS-TVA mouse model of spontaneous MBM and lung metastasis significantly decreased the incidence of detectable MBMs but did not affect primary tumor growth or the incidence of lung metastases. To clarify if OXPHOS promotes the formation of MBMs or …
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Transcriptional profiles of differentiating periocular neural crest cells and the function of Nephronectin during chick corneal development
… I performed functional studies by the RCAS-RNAi system. The knockdown of either NPNT or ITGα8 resulted in the reduction of corneal stromal thickness. Further studies revealed that NPNT overexpression upregulated cell numbers in the corneal stroma but did not increase cell proliferation. …