Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 87 for “"RC Internal medicine"”.
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A study of omega-3 fatty acid therapy in patients with nephrotic syndrome
Patients with nephrotic range proteinuria have a higher risk of cardiovascular disease through qualitative and quantative changes in lipids and lipoproteins. The aim of this study was to examine the effect of omega-3 fatty acids derived from fish oil in this population. Treatment with omega-3 fatty …
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Exacerbations, health status and sibling pair comparisons in severe Alpha-1-Antitrypsin Deficiency
… time, but show no relationship to changes in forced expiratory volume in one second (FEV1). However, despite lung function decline, patients do not show a progressive loss in health status. Index patients have worse lung function and health status and more emphysema than non-index siblings. …
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Development and validation of the BILAG-2004 Index for the assessment of disease activity in systemic lupus erythematosus
This research to develop and validate the BILAG-2004 index for the assessment of disease activity in patients with [systemic lupus erythematosus] SLE had involved several validation studies. The reliability of this index was shown in 2 exercises, as assessed by level of agreement, kappa statistic, …
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The genetics of type 1 diabetes: family and population studies
… lack of a large well-characterised clinical resource for study. This thesis describes how I have established a Repository of immortalised cell lines from large numbers of ethnically matched controls, sporadic type 1 diabetics and type 1 diabetic multiply affected families. The family resource is …
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Sensorimotor learning and control in autism spectrum disorders: The role of sensorimotor integration.
… autistic participants can successfully form new internal action models, but their movements are characterised by increased variability in the spatial position of peak acceleration. In Chapter Four, it was shown that autism participants were able improve their imitation of atypical biological …
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Development of an ergonomic risk assessment tool for work postures
The most widely used method for assessing work-related musculoskeletal disorders (WMSDs) is still the observational method, mainly because it is inexpensive and practical for use in a wide range of workplaces. However, there are no tools available that cover the wide range of physical risk factors …
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Evaluation of anti-gout potential of selected Malaysian medicinal plants
Gout is a type of arthritis that causes painful inflammation in joints due to the elevation of uric acid in the blood. Allopurinol is a common drug used for treating gout. However, due to unwanted side effects, new alternatives with fewer side effects are desired. The objectives of the study are to …
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Ethnobotanical and ethnopharmacological documentation of antimalarial plants used by the Jakun community in Kg Peta, Endau-Rompin, Johor, Malaysia
… validated the plants used in Jakun’s traditional medicine displayed promising therapeutic properties and further studies could lead to develop phytomedicines in the treatment of malaria.
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Arrhythmia heart disease classification using deep learning
Arrhythmia affects millions of people in the world. Sudden cardiac death is the cause about half of deaths due to cardiovascular disease and about 15% of all deaths globally. About 80% of sudden cardiac death is the result of ventricular arrhythmias. Arrhythmias may occur at any age but are more …
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Haemophilia 2010; an exploration of the lived experience of boys with haemophilia
There is a paucity of psychosocial research into living with haemophilia from a child’s perspective. Published works focus predominantly on the impact of HIV infection which occurred in the mid 1980’s. Since then treatment has been improved and intensified so that most children with severe …
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The emergency care of young people who self-harm: an exploration of attitudes towards young people who self-harm and the care they receive from practitioners working in pre-hospital and hospital based emergency services
… was not wholly clear. Findings from earlier research that had considered this were inconclusive and inconsistent (Dingwall & Murray 1983, White 2002). Methods: A mixed methods approach, using a triangulation convergent design was employed. Staff employed in four emergency departments in South East …
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Perceptions of illicit drugs and drug users: myth-understandings and policy consequences
… The core of the submission, eight papers researching the dangerous adulteration of illicit drugs, reflects these issues strongly. An area almost untouched by social science prior to this research these papers represent an attempt to pull together a range of evidence to inform more fully about …
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The development of self-injury as a multi-functional behaviour
… in using self-injury. The contribution this research has made towards developing our understanding of self-injury was addressed, particularly in relation to its use by the non-clinically defined members of the general public who took part, and in the context of advancing relevant nursing research …
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Phosphodiesterase 4 inhibitors for the treatment of inflammation associated with respiratory disease
… which is based upon a series of original research studies published between 1998 and 2002 focuses on the selection of novel phosphodiesterase 4 (PDE4) inhibitors for the treatment of inflammation associated with respiratory diseases such as asthma and chronic obstructive pulmonary disease. A …
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A contribution to developing the counselling and psychotheraphy profession: a reflexive action research study
… have been referred to as Schoolism, the research-practice gap and the hierarchy of evidence. I argue that it is important to address these phenomena as the profession moves towards statutory registration under the aegis of the Health Professions Council. I also argue that, in order to achieve …
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Studies of aldosterone renin ratio and genetic variation at the CYP11B1/CYP11B2 locus in human essential hypertension
… a novel automated plasma renin concentration (PRC) assay was evaluated in normotensive subjects and compared with the routinely used plasma renin activity (PRA) assay. The analytical and functional sensitivity, precision and stability of the new PRC assay were excellent. Overall, the correlation …
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The effects of statins on hypoxia-induced proliferation and cell signalling pathways in pulmonary artery fibroblasts
… proliferation of PAFs has been shown to be circulation specific and dependant on phosphorylation of p38 mitogen-activated protein (MAP) kinase, the cell signalling pathway(s)underlying this are incompletely characterised. Hypoxic activation of PAFs is a potential therapeutic target but, as p38 …
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Oxidative stress in endothelial cells of patients with coronary artery disease
… factor. Attempts to characterise cellular sources of elevated O2- production in the endothelium of patients with CAD revealed that while HSVEC endothelial nitric oxide synthase (eNOS) is not a major source of O2- generation in CAD, nicotinamide adenine (phosphate) dinucleotide (NAD(P)H) …
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The effect of epoch and cut-point on the assessment of physical activity levels in Kenyan school children
The aim of this study was to investigate the effect of using different accelerometer cut-points and epoch on reports of sedentary behavior and physical activity (PA) levels in a group of Kenyan school children. The PA levels of 26 children from the Nandi region of Kenya aged 4-16 years, was …
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Studies on the effects of movement on critically ill patients
No abstract available.
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