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Showing 1 to 1 of 1 for “"RBPjk-independent"”.

  1. RBPjk-Independent, NICD-Dependent Signals in Rbpj-/- Hair Follicle Keratinocytes Cause a Milder Phenotype in RBPjcKO Animals

    … gamma-secretase-dependent cleavage, and RBPjk-mediated downstream transcriptional activities of Notch receptors constitute the "canonical" Notch signaling pathway. This implies that loss of gamma-secretase (no Notch Intracellular Domain (NICD) release), Notch receptors (no NICD), or RBPjk

    wustl Repository record for RBPjk-Independent, NICD-Dependent Signals in Rbpj-/- Hair Follicle Keratinocytes Cause a Milder Phenotype in RBPjcKO Animals (opens in a new tab)