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Conformation of the U12-U6atac snRNA Complex of the Minor Spliceosome and Binding by NTC-related Protein RBM22

Ciavarella, JoannaThe Graduate School and University Center of The City University of New York2022

… assays show that the human spliceosomal protein RBM22, implicated in remodeling the human U2-U6 snRNA complex prior to catalysis but not yet definitively identified in minor spliceosomes, binds the U12-U6_atac snRNA complexes specifically and with similar affinity as to U2-U6 snRNA (a …

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