Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 52 for “"RBD"”.
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Analysis of rbd palm olein abrasive blasting as new metal surface cleaning method
… to metal surface. In this study, analysis of RBD palm olein as an alternative to the use of water in wet abrasive blasting process was investigated. The analysis in this study covers performance of cleaning process, personal dust exposure reduction, emission rate reduction and corrosion …
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Sub-Picomolar Detection of SARS-CoV-2 RBD via Computationally-Optimized Peptide Beacons
… spike protein receptor-binding domain (SRBD). The beacons contain two peptides, together forming a heterodimer, and a binding ligand between them to detect the presence of S-RBD. In the absence of S-RBD (OFF), the peptide beacons adopt a closed conformation that opens when bound to the …
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Prevalenza del disturbo comportamentale del sonno REM (RBD) e possibili biomarcatori retinici innovativi di alfa-sinucleinopatia.
… comportamentale del sonno REM idiopatico (iRBD) è una parasonnia REM caratterizzata dalla presenza di comportamenti anormali durante il sonno REM, inclusi movimenti complessi e vocalizzazioni che spesso mimano il contenuto onirico. Rappresenta il più rilevante marker prodromico dello …
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Untersuchung der strukturellen Phasenübergänge und Domänenbildung in den ferroischen Modellsubstanzen RbH 2 PO 4 und RbD 2 PO 4
RDP (RbH2PO4) belongs to the well known family of hydrogen bonded ferroelectrics with the composition A(H,D)2XO4 (A=K,Rb,Cs,Tl and X=P,As). On KDP (KH2PO4), the root member of the family, Busch and Scherrer discovered in 1935 the ferroelectric behaviour. A rich number of works concerning the …
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Ecological insight into three neotropical deer species: A study of spatial and diel distributions of white-tailed, Central American red brocket, and Yucatan brown brocket deer in northern Belize, Central America
… American red brocket deer (Mazama temama; RBD), and Yucatan brown brocket deer (Odocoileus pandora; YBB). Notably, our study provides the first confirmed camera record and the first empirical information of the YBB in Belize. In Chapter 1, we used single-season occupancy modeling on WTD and …
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MCI IN RBD as a Distinct Clinical Entity: Comparative Evaluation of Diagnostic Frameworks and the cognitive domain as predictive factors of phenotypic conversion
Rapid Eye Movement Sleep Behavior Disorder (RBD) is a parasomnia characterized by loss of muscle atonia during REM sleep and the occurrence of dream-enacting behaviors, often associated with vivid and sometimes violent dreams. Increasing evidence supports that RBD represents an early clinical …
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Produção do domínio de ligação ao receptor do coronavírus da síndrome respiratória aguda grave 2 utilizando Komagataella phaffii
… entre ACE2 e o domínio de ligação ao receptor (RBD). A proteína S e o domínio RBD tem sido extensamente empregados em diversas aplicações biotecnológicas. O desenvolvimento de tecnologias nacionais para o controle da pandemia é de extrema importância para o enfrentamento da pandemia e preparo …
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Computational Analysis of Antibody Binding Mechanisms to the Omicron RBD of SARS-CoV-2 Spike Protein: Identification of Epitopes and Hotspots for Developing Effective Therapeutic Strategies
… that target the Omicron receptor binding domain (RBD) of the Spike protein. The study demonstrates that the Omicron variant harbors 23 unique mutations across the RBD regions I, II, III, and IV. Of these mutations, seven are shared between RBD regions I and II, while three are shared among RBD …
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Investigating K-Ras inhibition by α-helical peptides
… a Ral GTPase effector protein domain (RLIP76 RBD) template. A single hit from a selection of an α-helical peptide library against K-Ras(G12D) was found to bind K-Ras(G12D) with low micromolar affinity. Further characterisation revealed that this peptide (P39) displayed selectivity for the …
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Phenotyping Behavioral Disorders in REM Sleep: Study of Digital Biomarkers of Neurodegeneration
… and detection of REM Sleep Behavior Disorder (RBD), a recognized prodromal symptom of alpha-synucleinopathies, among which Parkinson's Disease (PD). By integrating computational approaches with physiological insights, this research presents novel tools and methods for identifying early-stage …
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Structural Basis of Bat and Raccoon Dog Angiotensin-Converting Enzyme 2 (ACE2) Receptor Recognition by Sarbecoviruses
… SARS-CoV-2 is why its receptor-binding domain (RBD) binds human angiotensin-converting enzyme 2 (ACE2) with high affinity despite limited apparent time for adaptation, and why some bat-derived RBDs paradoxically bind human ACE2 more strongly than bat ACE2. To address this question, we compared …
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Computationally Designed Peptide Binder and Molecular Beacon for SARS-CoV-2
… the viral spike protein receptor-binding domain (RBD). The peptide was derived utilizing the existing crystal structure of spike protein’s RBD and ACE2 to determine the linear peptide fragments that contributed the most to the binding energy of the complex. We tested these linear peptide fragments …
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RARE BLEEDING DISORDERS: INSIGHTS INTO CLINICAL PRESENTATION, LABORATORY PHENOTYPE, AND GENETIC CHARACTERIZATION
I disturbi emorragici rari (RBD) rappresentano circa il 3–5% di tutte le condizioni emorragiche ereditarie e comprendono carenze di fibrinogeno, protrombina e fattori FV, FVII, X, XI e XIII, per lo più ad ereditarietà autosomica recessiva. Questi disturbi derivano da varianti patogeniche nei geni …
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An Investigation of the Clinical Predictors of Impulse Control Disorders in Patients with Parkinson's Disease
… (EDS), and REM Sleep Behaviour Disorder (RBD) Symptoms were increased among patients with ICD compared to those without. Assessment of Anxiety, Depression, EDS, and RBD Symptoms should be incorporated into ICD intervention strategies for patients with PD.
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Untersuchung zur Stimmerkennung bei aphasischen und nicht-aphasischen Patienten
… damaged (LBD, aphasic) and right brain damaged (RBD, non-aphasic) patients in a voice recognition task. Subjects: A group of 20 patients from the departments of neuropsychological rehabilitation at various clinics in Bielefeld and Bad Oeynhausen (Germany) participated. The criterion for inclusion …
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Analysis, Optimization and Application of AAV Capsid Assembly using Escherichia coli
… in particular, its receptor-binding domain (RBD) containing the receptor-binding motif (RBM) mediates virus binding to the host cell receptor, and therefore RBD and RBM are lead candidates for SARS-CoV-2 subunit vaccine development. VLPs have been widely used in vaccine research due to their …
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Charakterisierung der Prototyp Foamyvirus Hüllglykoprotein Rezeptorbindungsdomäne
… Arbeit die PFV Env-Rezeptorbindungsdomäne (RBD) charakterisiert. Hierfür wurden rekombinante PFV Env-Immunoadhäsionsproteine verwendet und deren Bindungskapazitäten an Zielzellen in der durchflusszytometrischen Analyse bestimmt. Untersuchungen zeigten, dass sowohl die extrazelluläre Domäne …
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Immune response to and pathogenesis of porcine epidemic diarrhea virus
… third study, a putative receptor-binding domain (RBD) of PEDV was identified in the S1 region of the S protein via bioinformatics, comparative structural biology, and homology modeling for protein structure in comparison to alphacoronaviruses with known RBD sequence. A recombinant protein was …
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Nanomechanical Analysis of Coronavirus Spike proteins and Correlation with Infectivity and Lethality
… interaction between the receptor-binding domain (RBD) of its spike protein and the human cell receptor ACE2. As an increasing number of variants of SARS-CoV-2 circulates globally, estimates of infectiousness and lethality of newly emerging strains are important. Here, we provide a novel way to …
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CHARACTERIZATION OF THE INTERACTION BETWEEN HEPARAN SULFATE AND THE SPIKE (S) PROTEIN OF THE LATEST SARS-COV-2 VARIANTS
… (hACE2) and the receptor binding domain (RBD) that decorates the capsid of SARS-CoV-2. In fact, this event triggers the fusion between the cell and virus membranes. The RBD region (and, more broadly, the S1 subunit) contains several positively charged amino acids that are solvent-exposed …
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