Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"RAW 264.7 murine macrophages"”.
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The in vitro effects of diallyl trisulfide on osteoclast formation and function in RAW 264.7 murine macrophages
… differentiation and function by utilising RAW 264.7 murine macrophages. In this study, various methods were carried out to establish the effects of DATS on osteoclast formation and function in RAW 264.7 murine macrophages. Using a resazurin assay, 1-5 µM of DATS was shown not to affect the …
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Construction, characterization, and evaluation of CLH001 as a vaccine candidate against respiratory glanders
… growth kinetics in both culture media (LBG) and RAW 264.7 murine macrophages. Additionally unlike wt, CLH001 was deficient in Hcp1 production and was unable to induce multinucleated giant cells (MNGC) formation in both phagocytic and non-phagocytic cell lines. Intranasal (i.n.) administration of …
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The Potential Role for CapB in Pathogenesis of Francisella tularensis
… ligase (capB) in LVS has a reduced virulence in murine infection models. I wished to investigate whether Francisella novicida was capable of producing such a capsule and under which environmental conditions this capsule was made. I have created a site-directed mutant of the capB gene in …
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Combating Plague: Fighting a War on Two Fronts Through Vaccine Design and New Therapeutic Intervention
… drugs to identify molecules that rendered RAW 264.7 murine macrophages resistant to cytotoxicity induced by the highly virulent Yersinia pestis CO92 strain. Following in vitro screening, a total of 17 prioritized drugs were chosen for further evaluation in a murine model of pneumonic plague …