Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"RARG"”.
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The Role of Cleavage and Polyadenylation Spcific Factor 6 (CPSF6) in Hematopoiesis
… I contributed to related exploratory studies on RARG fusion genes reported in APLL. My efforts laid the foundation for future work on RARG fusions in leukemia.</p>
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The genetics of anthracycline-induced cardiotoxicity in cancer patients
… NCF4 (rs1883112): RAC2 (rs13058338) and RARG (rs2229774), and tested for correlation with clinical status and cardiac injury. Finally, a corollary study was conducted on a subset of patients in an attempt to determine whether cardiac biomarkers may be more sensitive measures of …
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The role of retinoic acid in glioma growth control
… glioma. Retinoic acid receptor genes RARA, RARB, RARG, retinoid X receptor genes RXRA, RXRB, RXRG, transcriptional co-activator genes EP300, NCOA1, NCOA2, transcriptional co-repressor genes HDAC2, NCOR1, and NRPI1 are all significantly lower in high grade glioma with an increase in the expression …
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Evaluating The Therapeutic Efficacy of Restoring Wild-Type P53 Activity In P53-Mutant Tumors
<p>The p53 transcription factor is the most frequently altered in human cancers usually via missense mutations that undermine its transcriptional activity. Clinically, <em>TP53</em> mutations have been shown to be remarkably predictive of refractoriness to treatment, resulting in poor outcome. …