Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"RACK1"”.
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Functions of the eukaryote-specific ribosomal protein Asc1 /RACK1 in gene-specific translational activity
… of ribosomal proteins with a focus on the RACK1 protein (Asc1 in yeast), a eukaryote-specific ribosomal protein with many proposed functions in both cellular signaling and translation. In Chapter 2, I will present evidence that the Asc1 protein is required for efficient translation of a …
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Regulation of Cell Migration by Integrin -Mediated Adhesion
… Through this approach, a cDNA with homology to RACK1, a receptor for activated protein kinase C, was identified. Interestingly, this cDNA was found to be a truncated form of RACK1 that has one of the putative PKC binding sites, but lacks C-terminal sequences required to bind integrin beta …
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MEK1 binds βarrestin1 directly, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization.
… (Fsk) and isobutylmethylxanthine (IBMX). RACK1, another PDE4D5 binding partner, mediates and initiates cell migration in many cell types and affects the activity of the c-Jun NH2-terminal kinase (JNK) signalling pathway, via its interaction with PKC. SUMOylation of proteins is an important …
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THE ROLE OF DOPAMINE D3 RECEPTORS IN THE CONTROL OF ALCOHOL INTAKE
… ethanol intake increased the expression of RACK1 and BDNF in both WT and D3R-/-; in WT there was also a robust overexpression of D3R. Thus, increased expression of D3R associated with activation of RACK1/BDNF seems to operate as a reinforcing mechanism in voluntary ethanol intake. …
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Insulin-like growth factor receptor activity in cancer biology & therapy responses
… interaction with the scaffolding protein RACK1 in the context Integrin signalling, and IGF- 1R kinase activity. Here we investigated the phosphorylation of the SFYYS motif and characterise the conditions under which this motif may be phosphorylated under. As phosphorylated residues, the …
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Control of Turnip yellows virus: Assessing impact on oilseed rape quality traits and dissecting circulative transmission by aphids
… processes are poorly understood. As the GPA Rack1 protein has been implicated in transcytosis of TuYV particles across the aphid gut barrier, PMRi was used to dissect its role in the circulative transmission process. This revealed that Rack1 may have a direct role in TuYV acquisition by GPA. …
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Identification of echinus and characterization of its role in Drosophila eye development
… coat protein Clathrin, the scaffolding protein RACK1 and the casein kinase I epsilon (Dco). Co-immunoprecipitation additionally identified an interaction between Echinus and Enabled. This work has revealed echinus to be an important regulator of cell sorting and adherens junction formation in …
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ASSESSING ENDOCRINE ACTIVE SUBSTANCES¿ IMPACT ON THE IMMUNE SYSTEM THROUGH IN VITRO STUDIES
… selezionati di interferire con l'espressione di RACK1 (recettore per la chinasi C attivata 1), considerato come un ponte tra il sistema immunitario e quello endocrino, in quanto la sua espressione è sotto il controllo degli ormoni steroidei. Tutti i composti sono risultati in grado di modulare …