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Showing 1 to 1 of 1 for “"RABGAP1"”.

  1. An Investigation into the Intracellular Trafficking and Processing Pathways of Amyloid Precursor Protein

    Eden, JessicaUniversity of Cambridge2024

    … the APP tail have been identified. This includes RABGAP1, a cytosolic small GTPase-activating protein (GAP). Work presented in this thesis demonstrates that the PTB domain of RABGAP1 can directly interact with a YENPTY motif in the APP tail. This interaction is essential for the physiological …

    cambridge Repository record