Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"RAB21"”.
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The interrelationship between the endosomal sorting regulators RAB21, Retromer and WASH complex
… membrane organisers such as Rab GTPases like RAB21. RAB21 is previously shown to influence the cargo sorting process of specific cargoes based on recent work from Pr Jean laboratory. The primary purpose of this project is to understand the interrelationship between the different endosomal …
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Structure/Function Studies on Vps9 domain-containing Ankyrin Repeat protein (VARP)
… in the cytosol. Varp has been shown to be a Rab21 GEF, a Rab32/38 effector and also helps to regulate VAMP7 fusion activity. Varp has more recently been proposed to bind to the Golgi tether golginA4, the kinesin motor Kif5a and the retromer complex subunit Vps29. The retromer core complex, …
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Caractérisation d’une autophagie dysfonctionnelle dans les cellules souches ou progénitrices adultes sur le devenir de la cellule intestinale
… De plus, la déplétion dans les entéroblastes de Rab21, régulateur de la fusion autophagosome-lysosome, induit une augmentation de la prolifération des cellules souches et une diminution de l’activité de Stat92E, possiblement par sa fonction dans l’autophagie. En somme, ces travaux mettent en …