Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"R9C"”.
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Mutations in Phospholamban Alter the Structure and Function of the Calcium ATPase Regulatory Complex
… failure including L39stop (L39X) and Arg9Cys (R9C). Alanine substitution of PLB C-terminal residues significantly altered FRET from PLB to PLB and SERCA to PLB, suggesting a change in quaternary conformation of PLB pentamer and SERCA-PLB regulatory complex. We also quantified a decrease in PLB …
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Towards the full molecular investigation of protein kinase a mediated catalysis by NMR spectroscopy.
… relaxation of the myocardium. Mutants of PLN (R9C-PLN and R14Del-PLN) have previously been shown to be linked with forms of the fatal hereditary disease, dilated cardiomyopathy. The molecular basis of disease in this situation could result from irregularities in the association of these PLN …