Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"R domain"”.
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Structure-Function Studies on Human Epithelial Cystic Fibrosis Chloride Channels Expressed in Xenopus Laevis Oocytes
… cassette protein, comprising two transmembrane domains, two nucleotide binding domains (NBD1, NBD2) and a regulatory (R) domain. Channel gating is controlled by R-domain phosphorylation and by ATP binding and/or hydroysis at the NBDs. Exon 13 of the CFTR gene encodes residues 590 to 830, …
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Studies of protein complexes involved in the adenylation cascade of the nitrogen signalling pathway in Escherichia coli.
… of the adenylylation cascade. A new central domain has been identified using ATase truncation constructs in activity assays and solubility trials. This new regulatory domain is flanked by two flexible Qlinkers, Q1 and Q2. Thus the topology of ATase can be represented as N-Q1-R-Q2-C. The N …
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Glycoprotein hormone receptors in sea lamprey (Petromyzon marinus): Identification, characterization and implications for the evolution of the vertebrate hypothalamic-pituitary-gonadal/thyroid axes
… I. Functional assays on lamprey GpH-R I/rat LH-R domain swapped chimeric receptors suggest that IGpH-R I domains conserved their function. Alteration of the 'hinge' or Signaling Specificity Domain (SSD) segment of IGpH-R I by insertion/replacement with rat corresponding fragments results in a …
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Structural and functional studies of the ATP-dependent Clp proteases in cyanobacteria
… complex. A C-terminal motif in ClpC (the R-domain) was also demonstrated as conferring the specificity for ClpP3/R association. In paper II, the subunit stoichiometry of the ClpP1/P2 proteolytic core was determined by non-denaturing mass spectrometry. The proteolytic core was composed of an …