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Showing 1 to 2 of 2 for “"R domain"”.

  1. Structure-Function Studies on Human Epithelial Cystic Fibrosis Chloride Channels Expressed in Xenopus Laevis Oocytes

    … cassette protein, comprising two transmembrane domains, two nucleotide binding domains (NBD1, NBD2) and a regulatory (R) domain. Channel gating is controlled by R-domain phosphorylation and by ATP binding and/or hydroysis at the NBDs. Exon 13 of the CFTR gene encodes residues 590 to 830, …

    rockefeller Repository record for Structure-Function Studies on Human Epithelial Cystic Fibrosis Chloride Channels Expressed in Xenopus Laevis Oocytes (opens in a new tab)

  2. Glycoprotein hormone receptors in sea lamprey (Petromyzon marinus): Identification, characterization and implications for the evolution of the vertebrate hypothalamic-pituitary-gonadal/thyroid axes

    … I. Functional assays on lamprey GpH-R I/rat LH-R domain swapped chimeric receptors suggest that IGpH-R I domains conserved their function. Alteration of the 'hinge' or Signaling Specificity Domain (SSD) segment of IGpH-R I by insertion/replacement with rat corresponding fragments results in a …

    unh-thes Repository record for Glycoprotein hormone receptors in sea lamprey (Petromyzon marinus): Identification, characterization and implications for the evolution of the vertebrate hypothalamic-pituitary-gonadal/thyroid axes (opens in a new tab)