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Showing 1 to 20 of 39 for “"Quinolines"”.
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Antiprotozoal quinolines containing electrophilic moieties
… compromised the efficacy of these antimalarial quinolines. Therefore the development of new efficient drugs is of critical importance. Extensive research has identified the cysteine proteases in malaria and other parasitic diseases as potential targets for new chemotherapy due to their critical …
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The Chemistry of The Pyrimido(4,5-B)quinolines
Made available in DSpace on 2014-12-05T19:36:11Z (GMT). No. of bitstreams: 1 0013504.pdf: 5096834 bytes, checksum: 6607692b555ccb0f2401b6ef19c301fa (MD5) Previous issue date: 1955
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Quinolines: Novel Synthesis and Derivatives of Heterocyclic Bioactive Agents
… desired. Synthesis of heteroring-unsubstituted quinolines, however, has historically presented more of a challenge. Herein is described a novel method of cyclizing anilines with acrolein diethyl acetal to form these desired structures. This method produces quinolines with various substitutions …
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Ruthenium catalysts for the synthesis of quinolines and enol esters
… cyclized with ketones or aldehydes, affording quinolines. The key step in this method is a hydrogen transfer reaction, which can be performed by either a ruthenium catalyst or merely a strong base. In the second part, ruthenium catalysts are used for the activation of the alkyne triple bond, …
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Diastereoselective Synthesis of Planar Chiral N-Substituted Ferrocenes Derived from Epimeric Imidazolones and their Application to Asymmetric Hydrogenation of Quinolines
… in the asymmetric hydrogenation of 2-substituted quinolines with enantioselectivities up to 80% at pressures as low as 5 atm.
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Syntheses related to the preparation of substituted glycosyl derivates of pyrrolo (3,2-f) quinolines : spectroscopic studies of acetylated glycosylamine derivatives
The synthesis of 25 acetylated glycopyranosylamine derivatives (15 of which are newly reported here) from substituted sugar derivatives and amines is described. Eleven different methods were employed in these syntheses. Of the compounds prepared, 15 are substituted glycosylindoline derivatives. The …
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A base modulated synthesis of indoles and quinolines, an expedient synthesis of salviadione, and chemoselective couplings en route to indoles and pyrroloindoles
… been utilized in the synthesis of indoles and quinolines from a common precursor. The same protocol has also been employed in the synthesis of the indole alkaloid Salviadione. A systematic investigation of chemoselectivity in Kosugi-Migita-Stille coupling reactions provided the basis for the …
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Study on cyclization reactions of heterocyclic compounds bearing ethynyl and formyl groups in close proximity to each other /
… 1,3–dihydrofuro[3,4–b]quinolines and 1H–pyrano[4,3–b]quinolines frameworks via regioselective acetalisation/cyclization reactions of 2,4–disubstituted 6–phenylethynylpyrimidine–5–carbaldehydes and 2–alkynylquinoline–3–carbaldehydes were developed. A relatively short and …
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Synthesis of o-isotoluenes, o-quinodimethanes, and benzoenynyl carbodiimides and their cyclizations to polycyclic and heterocyclic compounds
… and 1-lithio-1-alkynes.;6H-Indolo[2,3-b]quinolines were synthesized from N-[2-(1-alkynyl)- phenyl]-N'-phenylcarbodiimides via a thermally-induced biradical-forming reaction. The Pd-catalyzed cross-coupling reaction between methyl 2-iodobenzoate and 1-alkynes furnished methyl …
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Developing and Understanding Iridium-Catalysed Arene Borylation
… of novel substrates classes, in particular quinolines. The borylation of substituted quinolines highlighted interesting electronic selectivity of the reaction. The site of borylation can be directed by changing the nature of the substituent on the ring. DFT calculations have been conducted …
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Identification of fungal species causing powdery mildew on cucurbits, determination of the genetic and pathogenic variations of the fungi and their sensitivity to major powdery mildew fungicides
… mildew fungicides, including DMI, QoI, SDHI, quinolines, and cyflufenamid fungicides. To identify the species of powdery mildew fungi, powdery mildew infected leaves of C. melo, C. sativus, C. maxima, C. moschata, C. pepo, and L. siceraria were collected from California, Illinois, Indiana, …
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Synthesis of highly substituted benzo-fused nitrogen heterocycles via tandem benzannulation/cyclization strategies
… method for the synthesis of polysubstituted quinolines was established. In addition, a tandem strategy for the synthesis of carbazoles was developed and applied in the total synthesis of the carbazole alkaloid carazostatin as well as formal syntheses of the alkaloids carbazoquinocin C and …
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Design, synthesis and biological evaluation of novel tetra-substituted quinoline-3-carboxamides derivatives
Quinolines are well known naturally occurring heterocyclic compounds with nitrogen as a heteroatom. Quinolines are also one of the major classes of naturally occurring compounds and the interest in their chemistry is due to the wide range of their biological activities. The objective of the project …
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Stress relief: Exercising Lewis acid catalysis for donor-acceptor cyclopropane ring-opening annulations, a basis for new reaction methodologies
… pyrrolo[1,2-a]indoles, pyrrolo[3,2,1-ij]quinolines, pyrrolizines, and tetrahydrobenzo[ij]quinolizines. To demonstrate the utility of the methodologies devised, progress toward, (±)-rhazinicine, a natural product, is discussed. This dissertation is organized into six chapters: (1) an …
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Bildung und Nutzung multinuklearer Titanocenkomplexe mit N-heterocyclischen Brückenliganden
… from different points of view. Quinoxalines and quinolines have been shown to undergo dehydrogenative C-C coupling reactions to produce titanocene complexes of biquinoline and hexaazatrinaphthylene (HATN) derivatives. Trinuclear assemblies of titanocenecomlexes of C3-symmetric HATN-type ligands …
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