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Showing 1 to 20 of 62 for “"Quinine"”.
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Hydrophosphination of Vinylcyclopropane & Quinine for Metal Coordination Chemistry
… Chapter two explores the hydrophosphination of quinine, yielding chiral quininyl phosphine ligands, later converted into phosphine chalcogenides (P=S and P=O). These quininyl phosphine ligands were coordinated with iridium, rhodium, copper, and silver to produce metal complexes. Comprehensive …
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The action of quinine on protein metabolism, temperature function & respiratory exchange
1. A.critical review of the previous important work is given. It is shown that a large part of it loses its value on account of the large and toxic doses used in experiments, while in some cases fundamentally unsound methods were used in investigation of the problem.
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New Aspects in the Pharmaceutical Analysis of Quinine and Some of Its Oxidation Products // Нови аспекти във фармацевтичния анализ на Quinine и някои негови продукти на окисление
… of the qualitative analysis of the alkaloids quinine and quinotoxine – representatives of the general alkaloid set of cortex Chinae. Quinine is a pharmacopoeial representative currently used in the therapy of malaria, particularly in cases of its cerebral form. Quinotoxine has been used for …
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Taste-masked quinine formulations for flexible pediatric drug dosing in oral treatment of malaria
De meeste geneesmiddelen worden specifiek gecommercialiseerd voor volwassenen waardoor het gebrek aan pediatrische geneesmiddelvormen specifiek ontwikkeld voor kinderen een wereldwijd probleem is. Bijgevolg zijn zorgverstrekkers vaak genoodzaakt om voor pediatrische toepassingen geneesmiddelen te …
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Chemical diversification of the natural products quinine, abietic acid and pleuromutilin by ring distortion
… to the cinchona alkaloid natural product quinine towards the creation of a collection of complex and diverse small molecules. Chapter 3 details the ring distortion of the terpene natural product abietic acid and details strategies for the synthesis of derivative libraries from the products …
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The Observable Effects of Acetylcholine, Succinylcholine, D-tubocurarine and Quinine and Their Binary Combinations on Tardigrades
… succinylcholine, d-tubocurarine, and quinine on tardigrades and to compare these effects to known mammalian reactions. Evidence of synergism or antagonism is sought by combining each drug compound with the other three individually. Procedure. Three species of tardigrades (Milnesium …
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Mechanism of Inhibition of Transepithelial Sodium Transport in Frog Skin by Quinine and Quinidine (Noise Analysis, Cgs 4270, Basolateral Membrane)
… microelectrodes to assess the effects of quinine and quinidine on the electrophysiological characteristics of the Na('+) transporting epithelial cells of frog skin. Under control conditions with tissues bathed symmetrically with a Cl-HCO(,3) Ringer solution and short-circuited …
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Evaluation of the Quality of Artemether/Lumefantrine, Sulphadoxine/Pyrimethamine and Quinine Sulphate Tablets in Public and private Health Institutions in Lusaka District
… Sulphadoxine/Pyrimethamine and Quinine tablets in selected Public and Private Health Institutions in Lusaka District. A cross sectional design study was conducted using quantitative research method. 20 Public and Private Health Institutions were randomly selected, and 430 tablets …
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Evaluation of the Quality of Artemether/Lumefantrine, Sulphadoxine/Pyrimethamine and Quinine Sulphate Tablets in Public and private Health Institutions in Lusaka District
… Sulphadoxine/Pyrimethamine and Quinine tablets in selected Public and Private Health Institutions in Lusaka District. A cross sectional design study was conducted using quantitative research method. 20 Public and Private Health Institutions were randomly selected, and 430 tablets …
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An examination of the effects of the catalase inhibitor 3-amino-1,2,4-triazole on ethanol, food and water intake
… food while a concentration of 0.15% w/w of quinine sulfate was less preferred. These two concentrations of saccharin and quinine were used in experiment 1B to study the effects of AT on taste reactivity. Results of experiment 1B showed that AT significantly decreased food intake but not …
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Taste sensitivity, eating behavior, and body fatness of preschool children
… skinfolds were measured. Taste sensitivity to quinine sulfate and sucrose was assessed with paired-comparison tests. Eating habits and food preferences were examined via questionnaires and two-day food records. Analysis of data was by simple correlations, means, and analysis of variance. There …
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Development of novel strategies to combat multidrug resistance mediated by efflux transporters and intracellular bacteria
… a library of dimers based on emetine and quinine. This resulted in triazole bearing dimers that potently inhibited P-gp efflux. Bivalent quinine probes were also developed as potential mechanistic probes of P-gp. Further, the bivalent strategy was expanded to the antimalarial drugs …
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Effects of diversity training and a retention interval on neophobia and conditioned taste aversion
… access to either distilled water, sucrose, quinine, hydrochloric acid, saline, or the three flavors of sucrose, quinine, and hydrochloric followed one or 28-days later by testing for neophobia and training and testing for conditioned taste aversion to saline. At the one-day interval, …
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Antitumor activity of antimalarials in human breast cancer cells
… chloroquine, primaquine, quinidine as well as quinine induced hyperacetylation of histone H4 without inhibiting HDAC activity. These results indicate that an alkylamino-substituted quinoline ring might be important for acetylation of histone H4. Accumulation of lipid droplets was observed in …
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The preparation and characterization of diastereomeric (+)-quinicinol
… Although many have found to have some activity, quinine (I) (see Fig. 1) (obtained from the bark of the Cinchona tree) is still listed among the most effective (1, 3, 4). Consequently, there has been much study done on isomers and derivatives of quinine, where the vinyl group on C-3, various …
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Study on the effects of bitter taste receptor on the rat pulmonary artery
… of any potential variations on rat TAS2R genes. Quinine, denatonium, and dextromethorphan caused a concentration-dependent relaxation of the pulmonary artery pre-contracted with phenylephrine. Removal of endothelium had no effect in the concentration-response curves for quinine, denatonium, and …
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Base stable and basic ionic liquids for catalysis
… the lacuna of basic ionic liquids.<br/><br/>New quinine based ionic liquids were synthesised, including what I believe to be the first reported example of a room temperature quinine based ionic liquid. The thermal stability of all the prepared quinine ionic liquids was greater than 200 °C. …
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The effect of quinoline anti-malarial drugs on the endolysosomal and secretory pathways of plasmodium falciparum strain 3D7, dictyostelium discoideum and mammalian A549 cells
… amadiaquine, halofantrine, mefloquine and quinine on the endolysosomal systems in Plasmodium falciparum 3D7, Dictyostelium discoideum and A549 pulmonary cancer cells were examined.
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