Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"Quality-adjusted life year."”.
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Is SABR cost-effective in oligometastatic cancer? An economic analysis of SABR-COMET randomized trial
… A willingness-to-pay threshold of $100,000/quality adjusted life year (QALY) was used. SABR was cost-effective in the base case, at an incremental cost-effectiveness ratio of $37,157/ QALY gained over a lifetime horizon, as compared to the SoC. Therefore, administering SABR is cost-effective …
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Capability Well-being and Health: Monetary Valuation and Population Normative Data
… popularity for valuing non-market goods like quality-adjusted life year (QALYs). It is an approach that uses econometric regression analysis for the estimation of a shadow price for non-market goods. Moving beyond the QALY, capability instruments have in recent years been hailed for providing …
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Cost utility and budget impact analysis of bortezomib and lenalidomide for the treatment of relapsed/refractory multiple myeloma in the South African public health sector
… progression and dead) over a 15-year time horizon. Efficacy data was obtained from the MM009/010 and APEX trials, while utilisation rates were obtained from a European study. Other input data was sourced from local literature. Outcomes were reported in quality adjusted life years …
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Optimizing Value from Cardiac Rehabilitation: A Cost-Utility Analysis Comparing Age, Sex and Clinical Subgroups
… by clinical presentation, age and sex. Clinical, quality of life and cost data were provided by the Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) and TotalCardiology. Data on efficacy was obtained from a meta-analysis of randomized controlled trials. …
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Measure for measure. Outcome assessment of arthritis treatment in clinical practice
… outcome measure, the number needed to treat per quality adjusted life year gained (NNQ) and apply it in RA, PsA and SpA patients on anti-TNF treatment. Methods: Data were retrieved from the South Swedish Arthritis Treatment (SSATG) register. In patients with RA, PsA and SpA commencing treatment …
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Trends and health economic aspects of service delivery of glaucoma
… guidelines of performing 6 VFs in the first two years. The constructed model found the proposed practice to be cost effective at a willingness to pay ceiling ratio of £30,000 per quality adjusted life year (QALY), identifying an incremental cost effectiveness ratio (ICER) of £21,679. The findings …
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Behavioural Activation for Depression: a systematic review and controlled clinical trial
… rate and study level moderators (study quality, number of sessions, severity and level of training) were extracted and analysed. Based upon results of the meta-analysis a randomised controlled trial of clinical and cost effectiveness comparing BA delivered by non-specialist with …
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Outcome valuation in the economic evaluation of healthcare
… system, and society is assumed to be inequality-neutral. This thesis identifies and explains these assumptions and then focuses on testing two of them in the empirical chapters. The overall aim of the thesis is to explore the extent to which the current framework reflects population …
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ETHNO-RACIAL DISPARITIES IN HEALTH OUTCOMES: EVIDENCE FROM THE AGING POPULATION
… improving functional health, health status and quality of life at both individual and community levels. Chapter 2 examines racial and ethnic disparities in willingness to pay (WTP) for improved health among an aging population sample while also examining the impact of health status and risky …
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Health Utility Assessment Among Caregivers of Individuals with Multiple Sclerosis
… Utilities among MS caregivers (aged 18–44 years) were lower than population norms (0.83 vs. 0.91). Caregiver burden (objective and subjective), care recipient disability status, and avoidance and critical coping influenced caregiver utilities. The mean utilities were 0.83 and 0.74 for …
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The development of an English Health-Related Quality of Life (HRQoL) measure for very young children, to be completed by proxy
… morbidity and functional limitation is the quality adjusted life year or QALY, which incorporates time spent in a health condition and Health-Related Quality of Life (HRQoL) into the measure. This is of increasing importance in Low Income Countries (LIC) where programmes have been adopted …
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Economics of Osteoporotic Fracture Prevention and Care
… and variability of costs and health-related quality of life (HRQoL) data. However, there were limited up-to-date cost and HRQoL estimates for osteoporotic fractures in China. Therefore, I conduct studies in Chapter 3 and 4 to address this knowledge gap. In Chapter 3, based on electronic …
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Stepped Care for Smoking Cessation: A Cost-Effectiveness Analysis and Simulation of Future Outcomes
… changes in morbidity and mortality over the lifetime for four smoking-related diseases (ischemic heart disease, cerebrovascular disease, lung cancer, and emphysema) due to successful cessation. Here, the outcome of interest was incremental cost per quality-adjusted life year due to successful …
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Hälsopromotion i skolan. Utvärdering av DISA - ett program för att förebygga depressiva symtom hos ungdomar.
… used in Swedish schools for students aged 13-15 years. DISA is commonly offered to females, but at some schools, the intervention is also offered to males. In this study, the application of the intervention for both females and males is evaluated. Aim: The overarching aim of this thesis was to …
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Health, Healthcare, and Economic Impacts of Hospital-initiated Smoking Cessation Interventions
… payer’s perspective, what is the short-term (one year) and long-term (lifetime) cost-effectiveness of the OMSC intervention, as compared to a usual care condition, among high-risk smokers with chronic diseases? A cost-effectiveness analysis was completed based on a decision-analytic model to …
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Contemporary challenges in clinical pharmacy practice - medicines optimisation and medication adherence
… use of medicines is a vital step to improve the quality of care that patients receive while minimising healthcare costs. One of the top priorities in healthcare systems worldwide is to provide cost-effective healthcare and through this, to optimise healthcare resource utilisation. One of the …
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Childhood varicella vaccination: an evaluation of clinical effectiveness, safety and cost effectiveness in Ireland
… cost-effectiveness ratio (ICER) of €8,700 per quality-adjusted life year (QALY) gained. Relative to a one-dose strategy, a two-dose strategy would be less cost effective with an ICER of approximately €45,000 per QALY gained, with little difference in the cost effectiveness of a two-dose short …
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Minimally invasive treatment of venous insufficiency using endovenous laser ablation
… is very common and causes significant quality of life (QoL) impairment. Conventional open surgery featuring junction ligation, stripping of the axial vein and phlebectomy is known to offer significant benefits over conservative management; resulting in improved QoL. Additionally this …