Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 217 for “"Q Science (General)"”.
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Two stages hybrid model of fuzzy linear regression with support vector machines for colorectal cancer
… cancer patients who received treatment in general hospital with twenty five independent variables with different combination of variable types were considered to find the best models to predict the tumor size of CRC. The main objective of this study is to determine the best model to …
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Application of whole-cell biosensor for the impact of crude oil exploration on the environment of the Niger Delta
The discovery of crude oil in exportable quantities in Nigeria was greeted with overwhelming ovation and high expectations in terms of the wealth generation possibilities and economic growth for the region. However, 5 decades onwards, the Niger-delta terrain and its people have become disenchanted …
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When disaster strikes: human responses to wildfires and evacuation in the south of France and Australia
… an understanding of behaviours that may be generalised or regionally-specific • using the combined data to create regression models that predict behavioural outcomes such as the decision to evacuate and evacuation delay times • considering the potential for regression and evacuation models …
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Landing behaviour of the host seeking malaria vector anopheles coluzzii in response to host associated cues
v ABSTRACT Female mosquitoes of the genus Anopheles transmit the parasites responsible for malaria, one of the most serious vector-borne diseases, which affects one-fifth of the world population. Current malaria prevention relies heavily on vector control interventions, which are most effective and …
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Towards realising multimodal robots
Evolutionary Algorithms (EAs) have been applied in co-evolutionary robotics over the last quarter century. They simultaneously generate the robot body morphology and controller algorithm through artificial evolution. However, the literature shows that in this area, it is still not possible to …
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Generating datasets for anomaly-based intrusion detection systems in IoT networks
Over the past few years, we have witnessed the emergence of Internet of Things (IoT) networks that bring significant benefits to citizens, society, and industry. However, their heterogeneous and resource-constrained nature makes them vulnerable to a wide range of threats and an attractive target to …
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Detection of the uniqueness of a human voice: towards machine learning for improved data efficiency
The aim of this thesis is to characterise voice characteristics that can establish the identity of the person who is speaking, independent of the language used. The fundamental goal of the work is to understand how humans recognise a speaker. The voice parameters such as: speech rate, natural …
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Distributed intelligent systems for a swarm of robots
Area exploration is a task where a robot tries to gain information about an unknown environment. Exploring an unknown area is a challenging task for a group of robots as no pre-made map exists, leading to setting a suitable swarm formation compatible with the area to be explored. Having a suitable …
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Regulation of RNA polymerase III transcription by the ID1, ID2, ID3 and E47 proteins
RNA polymerase III (pol III) is responsible for transcribing a set of genes that are involved in protein synthesis, including transfer (tRNA) and 5S ribosomal RNA (5S rRNA). Pol III transcription levels are increased in many cancers, as increased protein synthesis is required for tumour growth. …
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Anti-GD1a antibody targeted disruption of the node of Ranvier in a mouse model of acute motor axonal neuropathy
Guillain-Barré syndrome (GBS) is a peripheral neuropathy characterised by acute flaccid paralysis. The axonal variant is associated with anti-GD1a ganglioside antibody-dependent, complement-mediated injury to the peripheral axon with conduction block. The blood-nerve barrier (BNB) relatively …
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An evolutionarily conserved regulatory mechanism for endosomal membrane trafficking
Membrane fusion in all eukaryotic cells is facilitated by the formation of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complexes; a process that is regulated by Sec1p/Munc18 (SM) proteins. Membrane fusion has been conserved through evolution and hence a lot or our …
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Investigation of the actin-membrane interaction at the leading edge and its influence on membrane diffusion
… cell types and could therefore be seen as a general^M feature of protrusion. Using Fluorescence Recovery After Photo-bleaching (FRAP)in B16 F1 cells, it could be shown that the diffusion of membrane anchored GFP (GFP-F) is significantly inhibited at the leading edge compared to lamellar …
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Promoting bridging axonal regeneration after spinal cord injury
Olfactory ensheathing cells (OECs) are amongst the best candidates for cell transplantation into lesions of the central nervous system. These specialised glial cells are found in the olfactory system and are associated with the physiological restoration of neuronal circuitry in the first cranial …
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The VH repertoire and clonal diversification of B cells in myositis and vasculitis
Autoimmune inflammatory reactions occur in a number of disorders to a variety of self antigens but the precise cellular and molecular mechanisms resulting in pathology are largely unresolved. In some instances T cell mediated reactions are thought to be the main contributors to disease mechanisms …
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Lipoic acid metabolism in Leishmania major
Protozoan parasites of the genus Leishmania are the causative agents of a complex of diseases referred to as leishmaniasis. Leishmania have a digenetic life cycle that involves a sand fly vector (promastigote stage) and a mammalian host (amastigote stage). The parasites reside within very different …
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The role of the lateral spinal nucleus in nociception
The lateral spinal nucleus (LSN), located in the dorsolateral funiculus, is an area that has been poorly understood, but has been implicated in nociception. To investigate the function of this nucleus, three broad areas were investigated: responses to nociceptive stimuli, neurochemical relations to …
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Asteroid hazard mitigation: deflection models and mission analysis
Small celestial bodies such as Near Earth Objects (NEOs) have become a common subject of study because of their importance in uncovering the mysteries of the composition, formation and evolution of the solar system. Among all asteroids, NEOs have stepped into prominence because of two important …
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Monitoring single heart cell biology using lab-on-a- chip technologies
Abstract There has been considerable interest in developing microsensors integrated within lab-on-a-chip structures for the analysis of single cells; however, substantially less work has focused on developing "active" assays, where the cell‘s metabolic and physiological function is itself …
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Single photon emission computed tomography: performance assessment, development and clinical applications
This is a general investigation of the SPECT imaging process. The primary aim is to determine the manner in which the SPECT studies should be performed in order to maximise the relevant clinical information given the characteristics and limitations of the particular gamma camera imaging system …
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