Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Pyruvate decarboxylase"”.
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Identification of pyruvate decarboxylase/indole pyruvate decarboxylase gene family members from Arabidopsis thaliana.
… cofactor-dependent metabolic enzymes, including pyruvate decarboxylase (PDC), indole pyruvate decarboxylase (IPDC), and acetohydroxy acid synthase. PDC is a critical enzyme in plant metabolism that regulates energy production especially during periods of anaerobic stress. IPDC has long been …
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Nitrite Mode of Action: The Inhibition of Yeast Pyruvate Decarboxylase and Clostridial Pyruvate:ferredoxin Oxidoreductase by Nitric Oxide and Menadione
Embargo set by: Seth Robbins for item 70267 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs
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Investigation of the Evolutionary Aspects of Thiamin Diphosphate-Dependent Decarboxylases
… synthase (AHAS) but in others, like pyruvate decarboxylase (PDC), it has lost this function completely. The work presented here focuses on ThDP-dependent decarboxylases. In this thesis, several evolutionary aspects of this group of enzymes will be examined including (i) the …
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Gene expression profile of ethanol-stressed yeast in the presence of acetaldehyde
… biosynthesis were more highly expressed, as were pyruvate decarboxylase genes. Interestingly, however, there was no significant increase in the expression of trehalose synthesis genes or genes encoding HSPs; genes which, in previous studies, appeared to be associated with acclimatisation to …
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Studies into Mg-preconditioning of brewer’s yeasts
… specific activity of the alcohologenic enzyme pyruvate decarboxylase was stimulated by Mg enrichment and a correlation between cellular Mg and PDC activity exists. This was especially evident in Mg acetate preconditioned cells. Mg ion homeostasis in Mg non-and preconditioned yeast cells was …
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The design and synthesis of a novel thiamine cofactor for potential biocatalysis
… of some model compounds and their testing in pyruvate decarboxylase enzyme was successfully completed. Results indicated that only smaller chains are accommodated in the active site and initial attempts to synthesis a tertiary amine tether proved difficult because of intramolecular …
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Production of 1-butanol and butanol isomers by metabolically engineered Clostridium beijerinckii and Saccharomyces cerevisiae
… engineering and metabolic engineering of pyruvate decarboxylase (Pdc)-negative S. cerevisiae were performed to increase the production of butanol isomers by eliminating ethanol production. The metabolically engineered Pdc-negative S. cerevisiae containing heterologous 2,3-BD biosynthetic …
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Engineering microorganisms for synthesizing value-added products
… than ethanol, ethanol producing genes (PDC: pyruvate decarboxylase, ADH: acetaldehyde dehydrogenase) should be mitigated in S. cerevisiae. Due to the redox imbalance, S. cerevisiae exhibited low growth rate and glucose consumption rate, resulting in a failure to reach the productivity of a …
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In situ Lokalisierung, PGPR-Effekt und Regulation des ipdC-Gens der Azospirillum brasilense Stämme Sp7 und Sp245 bei verschiedenen Weizensorten, sowie endophytische Kolonisierung durch Herbaspirillum sp. N3
… the expression of the key gene ipdC (indole-3-pyruvate decarboxylase) was examined. For this, several methods were tested to generate a fusion of the ipdC promoter with a gfp or rfp reporter gene. Constructing a translational promoter fusion with the gfp variant mut3 on plasmid level made …
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Identification of up-regulated genes of the hyphomycete, Beauveria bassiana, during infection of Leptinotarsa decemlineata
… transporter), a presumed metabolic enzyme (pyruvate decarboxylase), a probable V-ATPase, two putative mucin-like proteins and a putative protein, which shares homology with an unknown ORF of the ascomycete N. crassa. Grown in the presence of its host cuticle, B. bassiana seemed to …
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2,3-butanediol production from cellobiose by engineered Saccharomyces cerevisiae
… alsS and alsD from Bacillus subtilis to convert pyruvate to 2,3-BDO via α-acetolactate and acetoin in engineered S. cerevisiae capable of fermenting cellobiose directly. Under oxygen-limited conditions, the resulting strain was able to produce 2,3-BDO. Still, the majority of carbon flux in the …
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Exploring the genetic mechanisms underlying superficial scald development and prevention in apple fruit during postharvest storage.
… such as malate, alcohol dehydrogenase, and pyruvate decarboxylase, leading to the accumulation of ethanol and acetaldehyde in both cultivars. The expression of three members of the VII subgroups of ERF genes was also observed in ‘Granny Smith’, which coordinate the acclimation process to …
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The architectural complexity of the human PDC core assembly
The mammalian pyruvate dehydrogenase complex (PDC) is a key multi-enzyme assembly linking the glycolytic pathway to the TCA cycle via the specific conversion of pyruvate to acetyl CoA and, as such, is responsible for the maintenance of glucose homeostasis in humans. PDC comprises a central …
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Structure and Molecular Biology of the Pyruvate Dehydrogenase Complex from Bacillus stearothermophilus
The pyruvate dehydrogenase multienzyme complex (PDHC) from the thennophilic, Gram-positive bacterium Bacillus stearothermophilus is assembled around a core of 60 copies of the dihydrolipoamide acetyltransferase (E2p) component, organized with icosahedral symmetry. The peripheral subunits, attached …