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Showing 1 to 3 of 3 for “"Pyruvate carrier"”.

  1. Molecular Determinant of Mitochondrial Shape Change

    … of glucose or supplementation of mitochondrial pyruvate carrier (MPC) transport blocker UK5099 and or carnitine-dependent fatty acid blocker etomoxir triggered an increase in the expression of MICU1, a regulator of the mitochondrial calcium uniporter (MCU) but not the MCU core subunit. …

    temple Repository record for Molecular Determinant of Mitochondrial Shape Change (opens in a new tab)

  2. In-vivo and in-vitro study of mechanism of action of 4 hydroxyisoleucine as an amino acid derived from fenugreek seed with anti-diabetic and properties

    … as well as inhibition of mitochondria pyruvate carrier. Real time monitoring of cell metabolism by Seahorse XF-24 autoanalyser after 24 hours incubation with 4-hydroxyisoleucine and isoleucine revealed that both 4-hydroxyisoleucine and isoleucine activities are strongly dependent on …

    london-metro Repository record for In-vivo and in-vitro study of mechanism of action of 4 hydroxyisoleucine as an amino acid derived from fenugreek seed with anti-diabetic and properties (opens in a new tab)

  3. Investigating the neuroprotective role of carboxyl-terminus of Hsc70-interacting protein (CHIP) in healthy aging

    … signaling cascade, as well as mitochondrial pyruvate carrier 1 (MPC1) and FIS-2, suggesting CHIP-associated mitochondrial dysfunction in chn-1-null animals. Membrane proteins as well as proteins associated with the regulation of trafficking activity, and more specifically retrograde …

    edinburgh Repository record for Investigating the neuroprotective role of carboxyl-terminus of Hsc70-interacting protein (CHIP) in healthy aging (opens in a new tab)