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Showing 1 to 5 of 5 for “"Pus10"”.
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STRUCTURAL AND FUNCTIONAL STUDIES OF ARCHAEAL BOX C/D GUIDE RNA AND ROLE OF A PUTATIVE HUMAN PSEUDOURIDINE SYNTHASE, PUS10 IN APOPTOSIS
… regular Archaeal one. Pseudouridine synthase 10 (Pus10) is the most recently identified Ψ synthase, found only in higher eukaryotes and Archaea. Archaeal Pus10 produces either tRNA Ψ55 or both tRNA Ψ54 and Ψ55 modifications. In Human, its Ψ synthase activity is not yet confirmed and interestingly …
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RECONSTRUCTION OF MOLECULAR REGULATORY NETWORKS IN <i>Arabidopsis thaliana</i>
… in function, and interaction specificity in Pus10 (EC 5.4.99.25) found in Archaea and Eukaryotes. Redundancy of Pus10 and the bacterial TrmA and TruB orthologs appear to have resulted in significant molecular evolution of Pus10 function. Neofunctionalization was identified in animal kingdom …
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Understanding the function and structure of herpes simplex virus type 1 pUL55, a novel immune evasion protein
… uncovered two viral tegument proteins (pUL13 and pUS10) as well as a cellular ubiquitin ligase (HUWE1) as candidate binding partners. The viral proteins pUL55, pUL13, and pUS10 were found to form a tripartite complex with both pUL55 and pUS10 interacting with pUL13. Expression of both pUL13 and …
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GUIDE RNA-DEPENDENT AND INDEPENDENT tRNA MODIFICATIONS IN ARCHAEA
… of archaeal tRNAs is catalyzed by the protein Pus10. An earlier study from our laboratory had shown that Pus10 from two different archaea, <italic>Methanocaldococcus jannaschii</italic> (MjPus10) and <italic>Pyrococcus furiosus</italic> (PfuPus10) have differential activities towards ψ54 …
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A TALE OF TWO METHYLATION MODIFICATIONS IN ARCHAEAL RNAs
… jannaschii (Mj1640), purified enzyme Pus10 from M. jannaschii and full-size tRNA transcripts or TØ-arm (17-mer) fragments as substrates, the sequential pathway of m1Ø54 formation in Archaea was reconstituted. The methylation reaction is AdoMet-dependent. The efficiency of the methylase …