Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Purine metabolites"”.
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Investigation of a suppression of asymmetric cell kinetics (SACK) approach for ex vivo expansion of human hematopoietic stem cells
… culture. The method, which involves the use of purine metabolites to achieve suppression of asymmetric cell kinetics, is referred to as SACK. The utility of the p53-dependent pathway was investigated for directing expansion of human HSCs. In order to support this investigation, the proliferation …
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Biomolecular engineered sensors for diagnostic applications
… (Chapter 5), anti-oxidants (Chapter 6), purine metabolites (Chapter 8) and phosphate (Chapter 9). Each chapter highlights a different aspect and applicability of the composite and go from simple physical surface modification (Chapter 5) to the incorporation of chemical agents (Chapter 6) …
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Investigating pseudohypoxia in renal cells deficient in fumarate hydratase.
… cells. Importantly, a novel link between purine metabolites, hypoxia, and Hif was discovered in Fh1-deficient cells, which may have important ramifications for tumorigenesis, driven by FH loss.
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Effect of Procedural Pain on Purines, MDA and Allantoin in Premature Infants
… morbidity on the urinary concentration of purines and allantoin. We found infants born at earlier gestational ages had significantly higher urinary purine and allantoin concentrations compared to infants born at later gestations, after 31 weeks. Weight for gestational age also altered the …
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Targeted and untargeted metabolomic profiling of human serum, urine and brain by liquid chromatography mass spectrometry (LC-MS)
… 3 where there was no exercise intervention.;The metabolites affected by the exercise included a range of purine metabolites and several acyl carnitines. Some metabolites including bile acids and several amino acids were subject to diurnal variation during the rest day (day 1). Using OPLS …