Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 31 for “"Pulmonology"”.
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The Clinical Spectrum, Aetiology and Disease Progression of Children with Post-infectious Bronchiolitis Obliterans at Tertiary Paediatric Pulmonology Service in Cape Town, South Africa
… years with PIBO attending a tertiary paediatric pulmonology service in Cape Town, South Africa over period of one year (November 2019 to October 2020). Results: Fifty-one patients with PIBO were enrolled, 78% were males, median age 60 months (IQR 33-107). The median age at disease presentation …
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MPhil in pulmonary haemorrhage in children in Cape Town
… on children attending a tertiary centre pulmonology clinic from the period 2000-2022. A review of the clinical data, investigations and lung biopsy results was done and outcomes were reported. Results: Sixteen children were included in the study. The median age at presentation was 1.79 …
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Pulmonary Alveolar Proteinosis: The first South African insight into this rare disease
… 11 patients with PAP were identified using the Pulmonology whole lung lavage register. A retrospective folder review was undertaken for demographic and clinical data which was captured via a paper data capture sheet and then entered into a REDCap database for ease of statistical analysis. …
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The prevalence of Legionella and mycoplasma seropositivity in the elderly in Cape Town
… guidelines published by the South African Pulmonology Society. There is no indication for the routine use of agents active against Legionella or mycoplasma. Clearly, these antibiotics should be introduced if specific pointers to infection with one of these organisms are found. Because of …
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The Use of Osteopathic Manipulation in a Clinic and Home Setting to Address Pulmonary Distress as Related to Asthma in Southwest Virginia
… study which took place in family practice, pulmonology, and asthma specialist offices in southwest Virginia. The intervention was a ten-minute semi-individualized OMT protocol and a self administered home OMT education session. Variable baseline, within-subject study design was utilized, …
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Early sequelae of post COVID-19 lung disease in patients who were mechanically ventilated for severe COVID-19 pneumonia
Introduction: COVID-19 resulted in an unprecedented worldwide spike in hospital and ICU admissions; predominantly for adult respiratory distress syndrome (ARDS). Survival rates for patients requiring mechanical ventilation in Cape Town during the waves driven by the ancestral strain and beta …
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The relationship between clinical trial participation and inhaler technique errors in asthma and COPD patients
Background Incorrect inhaler use is associated with poorer health outcomes, reduced quality of life, and higher healthcare utilisation in patients with asthma and COPD. Method We performed an observational study of pressurized metered-dose inhaler technique in patients with asthma or COPD. Patients …
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Cystic fibrosis in black African children in South Africa: a case control study
Background Cystic fibrosis (CF) is described more commonly in Caucasian populations in whom p.Phe508del is the most common mutation. There is a paucity of data of CF in black African children. The aim of this study was to describe and compare the presentation and outcomes of black African children …
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Building capacity for diagnosis of Primary Ciliary Dyskinesia in South Africa: a descriptive study
Background: Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterized by abnormal cilia motility. Diagnostic capacity for PCD in sub-Saharan Africa (sSA) is limited; and incidence of PCD and genotype in sSA is unknown. Objectives: To determine the prevalence of PCD in children and …
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The Effects of Progressive Relaxation and Myoelectric Feedback on Respiratory Resistance in Bronchial Asthmatics
<p>For the individual with bronchial asthma, an asthmatic attack can be a life threatening experience. A theory of bronchial asthma as a conditioned response has been recently proposed by several investigators. It was suggested that this conditioned response may be modified by lowering the arousal …
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The development and validation of a respiratory guideline for nurses in primary care in South Africa
The Practical Aproach to Lung Health in South Africa (P ALSA) initiative aims to improve the diagnosis and management of patients with respiratory diseases in primary care. An algorithm-based syndromic guideline integrating common respiratory diseases for nurses was developed after review of a …
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Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension
The diagnosis of primary pulmonary hypertension (PPH) and prediction of its course, whether treated or untreated, presents several problems. These are of particular relevance when selection of patients for, and timing of heart-lung transplantation is being considered. I performed a retrospective …
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Microbiological, genomic and transcriptomic analyses of human tuberculosis lung cavities
BACKGROUND: Tuberculosis (TB) remains out of control globally. Recent promising vaccine candidates have failed in clinical trials and host immunity in the lung remains poorly understood. Pathogenesis of pulmonary cavitation, the basis of TB transmission, is poorly understood. The degree of …
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Novel and newer nucleic acid amplification tests for the diagnosis of TB
Background: Current tools for TB diagnosis have suboptimal accuracy, perform poorly in diagnosing extra-pulmonary TB, and are not point of care; hence results have a slow turn-around time. Objective: This project evaluated the diagnostic accuracy of the promising novel loop mediated isothermal …
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Indoor air pollution and environmental tobacco smoke exposure in a South African birth cohort study
middleincome countries (LMIC) and a major reason for health care visits and hospitalisation. Environmental exposures to indoor air pollution (IAP) or tobacco smoke are important risk factors for childhood respiratory disease. Despite increased electrification, many communities in LMIC rely on …
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Early determinants of lung function in African infants
Childhood respiratory disease remains a major contributor of morbidity and mortality globally and both paediatric and adult chronic respiratory illness is increasing in prevalence worldwide. This burden of respiratory disease is heaviest in low-middle income countries (LMIC), areas that have a high …
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Evaluation of the costs of managing cutaneous adverse drug reactions to first-line TB therapy in South African TB patients
Background: Optimal tuberculosis (TB) treatment remains the backbone of effective TB control programmes. However, TB drugs are often associated with adverse drug reactions (ADR) that affect treatment adherence and cure. Cutaneous adverse drug reactions (CADR) are more commonly associated with Human …
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Hut lung : a study of domestically acquired pneumoconiosis in rural women
Pneumoconiosis in rural Transkeian women termed "Transkei Silicosis" has been thought to be caused by silica inhaled while grinding maize by traditional methods (Palmer and Daynes, 1967). This study was undertaken to investigate the features and causes of hut lung. The range of clinical, …
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