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Showing 1 to 14 of 14 for “"Pulmonary arterial pressure"”.
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Effect of pulmonary arterial pressure and precipitation on reproductive performance in Angus heifers in south central Wyoming
… is a consequence of right sided heart failure. Pulmonary arterial pressure (PAP) scores are indicator traits of HAD, and can be used to diagnose cattle at risk for the disease, or animals in the early stages of pulmonary hypertension and (or) heart failure. There is concern that the …
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Pulmonary Artery and Central Venous Pressures as Prognostic Indicators of Post Lung Transplant Outcome
Background The relationship between elevated mean pulmonary arterial pressure (mPAP) and central venous pressure (CVP) on poor prognosis in patients undergoing lung transplants has been widely debated. We hypothesized that not only the isolated values of mPAP and CVP, but also the combination of …
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Accuracy of Noninvasively Determined Pulmonary Artery Pressure in Dogs With Myxomatous Mitral Valve Disease
Development of pulmonary hypertension is an independent predictor of poor outcome in dogs affected by myxomatous valvular degeneration (MMVD). Systolic pulmonary arterial pressure is routinely estimated by Doppler echocardiography applying the simplified Bernoulli equation to the velocity of …
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Elucidating the roles of endothelial PTBP1 and PKM2 in Pulmonary Arterial Hypertension: implications for therapy
Pulmonary Arterial Hypertension (PAH) is a rare, life-limiting disease with no cure, and is regarded the most severe form of pulmonary hypertension (PH). The disease is characterised by remodelling of peripheral pulmonary arteries, leading to increased mean pulmonary arterial pressure, right …
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Melatonin as a novel cardioprotective therapy in pulmonary hypertension
Pulmonary hypertension (PH) is characterized by elevated pulmonary arterial pressure which leads to right ventricular hypertrophy and failure. The mechanism involved in the pathophysiology of the disease remains unclear but it is suggested that oxidative stress may trigger cardiovascular …
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The Role of BMP9-Induced SEMA3G in Pulmonary Vascular Stability
The progressive disease, pulmonary arterial hypertension (PAH), occurs when the pulmonary vasculature pathologically remodels and constricts, causing increased pulmonary arterial pressure eventually leading to right heart failure. Loss of function mutations in the bone morphogenetic protein (BMP) …
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Development and Resolution of Pulmonary Arterial Hypertension in RAO Horses
… affected horses. Horses demonstrating severe pulmonary compromise develop concurrent secondary pulmonary hypertension. The development of pulmonary hypertension is well documented in RAO affected horses, however, it is not known how rapidly increases in pulmonary artery pressure occur after …
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microRNA-21 as a Pro-Fibrotic Mediator in Right Ventricular Failure
… congestive heart failure (HF) and secondary pulmonary hypertension. Ten non-paced dogs were used as normal controls. Hemodynamic and echocardiographic assessment confirmed development of RV dysfunction and secondary pulmonary hypertension in tachypaced dogs. In HF vs control, RV end-diastolic …
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Contribution of Causal Aquaporin-1 Mutations to the Pathobiology of Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a rare and debilitating disease characterised by elevated pulmonary arterial pressure and extensive vascular remodelling in the lungs, with a lack of effective curative options. The identification of genetic variations in genes encoding components of the …
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VENTILAZIONE MECCANICA E VOLUTRAUMA: STUDIO IN VIVO IN UN MODELLO SUINO
… animals was clearly related to the increase in pulmonary arterial pressure, which induced the extravasation of fluid into lung parenchyma. Moreover, we have evaluated the changes in lung mechanics and metalloproteinases production and activation in three different types of lung damages evoked by …
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Biochemical and Functional Investigations into the Contribution of SOX17 Mutations to the Pathogenesis of Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a rare fatal disease characterised by endothelial dysfunction and obliteration of small pulmonary arteries. The resulting increase in pulmonary arterial pressure and right ventricular afterload ultimately causes death by right heart failure. Current …
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Das endogene Cannabinoid Anandamid erhöht Cyclooxygenase-2-abhängig den pulmonalarteriellen Druck in der isolierten Kaninchenlunge
Die Wirkstoffe der Cannabis-Pflanze, die sog. Cannabinoide, können in vielen medizinischen Bereichen therapeutisch angewendet werden. Neben den eher unerwünschten psychotropen Effekten werden verschiedene Organsysteme komplex beeinflusst. Bei neurologisch-psychiatrischen Krankheitsbildern oder zur …
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The prevalence and risk factors associated with pulmonary arterial hypertension among HIV-infected individuals in a tertiary hospital in Durban
… health burden and a risk factor for developing pulmonary arterial hypertension (PAH). Africa carries the largest burden of HIV globally. However, data summarizing the epidemiology of PAH remains unclear. The lungs are often affected by disorders associated with HIV-infection. HIV-infected …
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Hämodynamische Auswirkungen synthetischer, pflanzlicher und endogener Cannabinoide im Modell der isolierten Kaninchenlunge
Cannabinoide zeigen komplexe kardiovaskuläre Effekte. Das endogene Cannabinoid Anandamid (Arachidonylethanolamid) induziert in verschiedenen Organsystemen eine hauptsächlich über periphere CB1-Rezeptoren vermittelte Vasodilatation. Der Einfluss von Cannabinoiden auf die pulmonale Strombahn ist …