Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 89 for “"Pulmonary Tuberculosis"”.
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Pulmonary Tuberculosis: towards improved adjunctive therapies
The potential to improve pulmonary tuberculosis (PTB) treatment outcomes with adjunctive immunotherapies requires investigation. L-arginine and vitamin D have antimycobacterial properties which render them suitable candidates. Therefore the Arginine and Vitamin D Adjunctive therapy in Pulmonary TB …
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Pulmonary Tuberculosis: towards improved adjunctive therapies
The potential to improve pulmonary tuberculosis (PTB) treatment outcomes with adjunctive immunotherapies requires investigation. L-arginine and vitamin D have antimycobacterial properties which render them suitable candidates. Therefore the Arginine and Vitamin D Adjunctive therapy in Pulmonary TB …
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Pharmaceutical care for pulmonary tuberculosis treatment in Thailand
… cohort study collecting data from 1,398 pulmonary TB patients who started treatment between October 2010 and September 2013. Project 3 was a prospective study collecting data from 104 pulmonary TB patients who started treatment between January and May 2014. The propensity score matching …
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Drug discovery at the site of pulmonary tuberculosis
The protracted duration of standard tuberculosis (TB) therapy suggests the inadequacy of current first line TB drugs to eliminate the causative agent Mycobacterium tuberculosis (Mtb). Among multiple potential causes, this may be due to poor distribution of TB drugs into the pulmonary lesions in …
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Mycobacterium W immunotherapy for treating pulmonary tuberculosis : a systematic review
Tuberculosis (TB) remains a major health problem in the developing world, accounting for approximately 2 million deaths per year. The search for appropriate and applicable therapies to reduce the burden of TB is essential. Mycobacterium w (M w) is a heat-killed immune-modulating vaccine designed to …
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Interferon-γ aptamers for the diagnosis of extra-pulmonary tuberculosis
Tuberculosis (TB) is a major global health problem. About 15-20% of the global population who are HIV negative have extra-pulmonary TB (EPTB) such as pleural TB. This increases to 50-70% in HIV positive people. The diagnosis of EPTB is challenging because of the low bacillary burden. Interferon …
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Aerosolizable Drug-Loaded SPIONs for Treatment and Diagnosis of Pulmonary Tuberculosis
Tuberculosis (TB) remains one of the most pressing global infectious diseases, with the rise of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains presenting significant challenges to current therapeutic strategies. Existing treatment regimens are prolonged, systemically toxic, …
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Effect of diabetes and HIV on radiographic manifestations of pulmonary tuberculosis
… a significant risk factor for the development of tuberculosis. Early detection and treatment of tuberculosis is essential to prevent unwarranted morbidity and mortality. This hinges on efficient diagnostic methods and tools. The chest radiograph remains a cornerstone in pulmonary tuberculosis …
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The role of IL-4 and Th2-like cytokines in pulmonary tuberculosis
Tuberculosis (TB) vaccine candidates have been mostly ineffective and it remains unclear as to what constitutes protective host immunity. Despite high levels of IFN-γ at the site of disease, the Th1 cytokine associated with protection, many individuals still have progressive active TB. Whether a …
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Assessment of airway compression on chest radiographs in children with pulmonary tuberculosis
Study rationale: Diagnosis of pulmonary tuberculosis (PTB) in children relies heavily on chest radiography as sputum samples are difficult to obtain and only yield positive results in 30-74% of children treated for PTB. However, radiological signs between lower respiratory tract infections (LRTI) …
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Development and in vivo Analysis of Inhaled Clofazimine for the Treatment of Pulmonary Tuberculosis
Tuberculosis (TB) is a leading cause of death globally, despite current treatment options. The old and rarely used oral antibiotic, clofazimine (CFZ), is a potentially viable treatment option against TB infections due to its activity against TB, multidrug-resistant TB (MDR), and extensively …
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The clinical significance of the erythrocyte sedimentation rate with special reference to pulmonary tuberculosis
There are few subjects in medicine, about which there is more controversy than the Erythrocyte Sedimentation Rate. Some authorities place great ·reliance on test while others have discarded it as having no practical importance. There is little agreement as regards either the methods of estimation …
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Pulmonary tuberculosis in the elderly : diagnostic criteria and its epidemiology in old age homes
… were primarily infected with Mycobacterium tuberculosis at a time when no effective chemotherapeutic treatment was available. With the progressive decline in cell mediated immunity that accompanies aging, the potential to reactivate a dormant lesion, or to be re-infected increases. The …
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Diagnostic Accuracy of Nucleic Acid Amplification Tests in Urine for Pulmonary Tuberculosis: A Meta-Analysis
… To determine the diagnostic accuracy of tuberculosis nucleic acid amplification tests (NAATs) in urine samples for active pulmonary tuberculosis (PTB). <bold>Design:</bold> Systematic review and meta-analysis. Electronic databases and reference lists were searched without language, …
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Characterizing population pharmacokinetic/pharmacodynamic relationships in pulmonary tuberculosis infected adults using nonlinear mixed effects modelling
… OFLOTUB study investigating the shortening of tuberculosis treatment. A total of 343 adults enrolled in Benin, Guinea, Senegal, and South Africa were randomized to receive rifampicin, isoniazid, pyrazinamide, and ethambutol in the standard 6-month control regimen or the 4-month test regimen …
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