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Showing 1 to 20 of 21 for “"Pullulan"”.
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Pullulan w-carboxyalkanoates for Drug Nanodispersions
Pullulan is an exopolysaccharide secreted extracellularly by the black yeast-like fungi Aureobasidium pullulans. Due to an alpha-(1-->6) linked maltotriose repeat unit, which interferes with hydrogen bonding and crystallization, pullulan is completely water soluble unlike cellulose. It has also …
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Self-Assembly of Pullulan Abietate on Cellulose Surfaces
… in wood, a system composed of a model copolymer (pullulan abietate, DS=0.027) representing the lignin-carbohydrate complex (LCC) and a model surface for cellulose fibers was used. The self-assembly of the polysaccharide pullulan abietate (DS=0.027) onto a regenerated cellulose surface prepared …
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Synthesis of New Pullulan Derivatives for Drug Delivery
Pullulan is a non-ionic water-soluble polysaccharide which is produced from starch by the yeast-like fungus Aureobasidium pullulans. Pullulan is known for its non-toxicity and biocompatibility. Most pullulan modifications are intended to reduce its water solubility or to introduce charged or …
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The development of chemically engineered pullulan for drug delivery
Pullulan has been chemically modified by the incorporation of various hydrophobic molecules, to produce two types of derivatives (hydrophobically modified carboxymethyl pullulans (HMCMPs), and crosslinked carboxymethyl pullulan). The foregoing modifications were performed in two steps from the …
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Enzymes involved in utilization of pullulan by Bacteroides thetaiotaomicron
A pullulanase I gene from Bacteroides thetaiotaomicron has been cloned. To determine whether the cloned pullulanase gene was essential for pullulan utilization, I used directed insertional mutagenesis to inactivate the B. thetaiotaomicron pullulanase gene.
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Preparation and characterization of fast dissolving pullulan films containing griseofulvin nanoparticles for bioavailability enhancement
… through preparation of drug nanoparticle-laden, pullulan-based strip films. The work entails (i) wet-milling griseofulvin in a stirred media mill using pullulan (polymer) along with sodium dodecyl sulfate (surfactant) as stabilizers, (i i) preparing strip films by casting-drying a precursor …
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La fermentation du glucose en vue d'obtenir le pullulan et l'application de concepts de génie chimique
… sucres sous l'action d'une levure le Pullularia Pullulans. Après une étude en discontinu sur erlen et "shaker" rotatif qui nous a montré que la viscosité la plus faible est obtenue avec le glucose, nous avons fait une étude sur "batch"• Cette dernière nous a permis de déterminer les relations …
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Studies of Interactions Between Rod-like Celulose Nanocrystals and Xylan and Pullulan Derivatives: A Light Scattering Study
… whiskers obtained from cotton. Adsorption of pullulan 4-chlorocinnamate (P4CC03) onto cellulose nanocrystals (DOE-2-12B) was also studied by UV-Vis spectroscopy, zeta-potential measurements, and polarized and depolarized dynamic light scattering. UV-Vis spectroscopy of the P4CC03/water binary …
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Preparation of polysaccharide-based nanoemulsions to reduce melanoma drug resistance and inflammation markers
… and characterisation of alginate, chitosan, and pullulan nano-emulsions as a delivery platform to target melanoma. In this study, a novel nano-emulsion delivery system was designed and optimised using a series of experimental steps including, in vitro drug release, cell viability (MTT), Cellular …
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Biochemical characterisation of an alpha-amylase with pullulan hydrolase type III characteristics derived from a hot spring metagenomics library
… biochemically characterise a putative type III pullulan hydrolase (PHTIII). A sequence-based metagenomic screen from previous performed by Xiao Ping Hu (2010) was used to identify novel glycosyl hydrolase enzymes in shotgun metagenomic sequence data from the Mphizi hot spring in Malawi. An …
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The Influence of Selected Novel Glucose -Based Polymers on Nutrient Digestion, Glycemic and Insulinemic Responses, Colonic Fermentation Characteristics, and Ileal and Colonic Microflora Concentrations in the Adult Canine and (Or) Human
… the nutritional effects of including pullulans and 7-cyclodextrin in the diet of healthy adult canines and humans. Pullulan is a linear homopolysaccharide of glucose that is an alpha-1,6 linked polymer of maltotriose subunits. Pullulan is synthesized intracellularly and secreted by the …
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Microencapsulation of an omega-3 polyunsaturated fatty acid source with polysaccharides for food applications
… and blends of chitosan, high-amylose starch, and pullulan as wall materials. The primary objectives of this research were (1) to evaluate the effect of chitosan type and oil:wall ratio on ω3 PUFA microcapsule properties, (2) to evaluate the effect of blending chitosan with high-amylose starch and …
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Designing a safe dendronised polymeric nanocarrier for hydrophobic drugs or gene delivery in cancer therapy
… system characterised by different hydrophilic pullulan derivatives segments were then synthesised using Huisgen azide-alkyne 1,3-dipolar cycloaddition between pullulan (P), lactosylated pullulan (P(Lac)) and pullulan bearing disulphide linkage (PSS) with the G3 dendron to lead amphiphilic block …
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Studies of Biomacromolecule Adsorption and Activity at Solid Surfaces by Surface Plasmon Resonance and Quartz Crystal Microbalance with Dissipation Monitoring
… shear moduli of ~ 105 N·m-2. Adsorption of pullulan 3-methoxycinnamates (P3MC) and pullulan 4-chlorocinnamates (P4CC) with different degrees of cinnamate substitution (DSCinn) onto cellulose, cellulose acetate propionate (CAP), poly(L-lactic acid) (PLLA), and methyl-terminated self-assembled …
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Studies of polysaccharide adsorption onto model cellulose surfaces and self-assembled monolayers by surface plasmon resonance spectroscopy
… and cellulose/water interfacial properties of pullulan (P) and pullulan cinnamates (PCs), 2-hydroxypropyltrimethylammonium xylans (HPMAXs), and hydroxypropyl xylans (HPXs). Hydrophobic modification of pullulan with cinnamate groups promoted adsorption onto model surfaces of regenerated …
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Structural characterization and bacterial degradation of marine carbohydrates
… of degradation experiments with polysaccharides (pullulan, laminarin) showed that they are degraded by bacteria at virtually the same rate as structurally related substrates in the molecular weight range of 300-600 daltons. Degradation of the branched glucan and the teichoic acid-type …
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Synthesis and Characterization of Drug-Containing, Polysaccharide-Based Nanoparticles for Applications in Oral Drug Delivery
… several novel cellulose derivatives and a pullulan derivative were studied. Among these polymers, carboxymethyl cellulose acetate butyrate (CMCAB)-drug nanoparticles were investigated in detail. Previous work has shown that the presence of different chemical groups in CMCAB could aid in …
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Über lasergeheizte kolloidale Goldnanopartikel in Polymerlösungen
… visualisiert. Der Soret-Koeffizient des Systems Pullulan/Wasser weist temperaturabhängig einen Nulldurchgang auf. Dadurch entstehen komplizierte Szenarien zur Strukturbildung. Das Konzentrationsfeld wurde numerisch berechnet und diskutiert. Im Gegensatz zum Konzentrationsfeld von PS/Toluol ist es …
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Adsorption Studies of Polysaccharides and Phospholipids Onto Cellulose
… monolayers on gold. The adsorption of pullulan cinnamate (PC) onto cellulose surfaces increased with increasing degree of cinnamate substitution. The interactions between PCs with higher degree of substitution (DS) and porous nanocrystalline cellulose (NC) films presumably generated …
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Formulation of Biodegradable Polysaccharide Blend as Replacement of Single-use Plastics
The accumulation of plastic waste has long been a problem and requires a multifaceted approach to address the complexity of this issue. Two heavy contributors are single-use plastics in the form of food packaging, and medical packaging. Conventionally, these are made of petroleum-based plastics as …
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