Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 49 for “"Public databases"”.
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Identification of the virulence gene of Mycobacterium tuberculosis
… compiled and integrated information from various public databases to catalogue 246573 microbial genes from 84 organisms, including pathogens and non pathogenic microbes. We determined the phylogenetic distributions by grouping the proteins into families based on sequence similarity with the aid of …
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Error Correction for High-Dimensional Data via Convex Programming
… addition to achieving excellent performance on public databases, this approach sheds light on several important issues in face recognition, such as the choice of features and robustness to corruption and occlusion.
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Clinical Interpretation of Novel Copy Number Variations
… diagnostic technique in the clinic, and several public databases of well-characterized CNVs are being compiled, but a standard for interpreting uncharacterized CNVs has yet to emerge. This thesis examines the clinical interpretation of uncharacterized CNVs as a multiple instance binary …
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Analysis of Genes Expressed by Meloidogyne incognita Males: Generation of ESTs and Comparative Genomics
… of genes expressed by these males. Searching the public databases for homologous sequences providing a second degree of clustering and provided the putative identification of genes identified by these clusters. Approximately 89% of the clusters had significant homology to the public databases and …
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Machine learning models for functional genomics and therapeutic design
… design, two areas with ample data deposited in public databases and tremendous clinical implications. The shared theme of these models is to learn how the composition of a biological sequence encodes a functional phenotype and then leverage such knowledge to provide insight for target discovery …
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DNA Microarray Data Analysis and Mining: Affymetrix Software Package and In-House Complementary Packages
… provides rapid connection to many online public databases, as well as the integration of the original microarray data, relevant publications and other useful information. The in-house programs allow investigators to process and analyze the full Affymetrix microarray data in a speedy manner.
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How to Identify leading indicators for scenario monitoring
… correlation between various datasets from public databases, identifying, screening then consolidating the key driving forces of particular business scenarios. This process, in concert with a thorough qualitative assessment by business leader practitioners, enables an effective practice of …
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De novo Sequencing and Analysis of <em>Salvia hispanica</em> Transcriptome and Identification of Genes Involved in the Biosynthesis of Secondary Metabolites
… contents. Despite these benefits and its growing public demand, very limited gene sequence information is currently available in public databases. In this project, we generated 90 million high quality 150 bp paired-end sequences from the chia leaf and root tissues. The sequences were de novo …
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Development of web-based supporting tools for generic diagnostic reservoir operation
… tools (DROT), is developed and deployed for public access. DROT implements generic rules and algorithms derived from analytical studies and general data mining techniques, and provides diagnostic information for a particular reservoir operation problem. In addition, auxiliary functionalities …
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Quantifying racial disparities in end-of-life care
… been reported previously are also present in two public databases. I explore the notion that one underlying cause of this disparity is due to mistrust between patient and caregivers, and develop a multiple trust metric proxies to measure such mistrust more directly. These metric demonstrate even …
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Isoform-Specific Variant and Expression Analysis of Epigenetic Genes in Neurodevelopment and Disease
… expression during neurodevelopment. Methods Public databases (ClinVar, gnomAD, Ensembl BioMart) were used to compute missense variant densities in non-overlapping, isoform-specific exons of EM genes. Genome-wide variant data were used to ensure sufficient coverage. Enrichment was tested using …
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Molecular evolutionary analysis of the American pika (Ochotona princeps)
… princeps</em> using draft genomes available from public databases. I constructed phylogenies using the two <em>O. princeps </em>alleles and homologs from other mammal species, and then used the CODEML module of PAML to detect evidence of selection along branches in the phylogeny. Four genes …
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A Bioinformatics Approach to Identifying Radical SAM (S-Adenosyl-L-Methionine) Enzymes
… amount of enzyme sequences that are available in public databases, but experiments to investigate what chemical reactions the enzymes perform take a great deal of time. In our work, we utilize Hidden Markov Models to identify possible radical SAM enzymes and predict their possible functions …
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Understanding co-expressed gene sets by identifying regulators and modeling genomic elements
… characterized gene sets from literature and public databases. However, few tools exist examining the non-coding, regulatory sequence of gene sets for evidence of a shared regulatory signature that may signal the involvement of important DNA-binding proteins called transcription factors (TFs). …
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Solar Roof Monetization in US Industrial Real Estate
… industry stakeholders and an extensive review of public databases and industry research reports, the research delineates the nuanced dynamics of the industrial solar market, marked by state-dependent variability and diverse regulatory environments, and business model for deployment. The study …
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Comparison of Subterranean Termite (Rhinotermitidae: Reticulitermes) Gut Bacterial Diversity Within and Between Colonies and to Other Termite Species Using Molecular Techniques (ARDRA and 16S rRNA Gene Sequencing)
… sequences from this study and sequences from public databases (1,450 sequences total), a neighbor-joining tree demonstrated strong evidence for coevolution of termites and their symbiotic bacteria, especially in the phyla Bacteroidetes, Actinobacteria, Spirochaetes, and "Endomicrobia." Many …
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Diversification of beaked redfish, Sebastes mentella, along a depth gradient in the central North Atlantic
… crossreferencedagainst data currently held in public databases. Results revealed the existence ofinaccurate reference sequences in data bases, likely stemming from speciesmisidentification from previous studies, which currently hinders the efficacy of DNAmethods for the identification of …
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Large Quasar Groups at Redshift ~ 2
This project aims to use the large public databases that are now becoming available in the Virtual Observatory. For my purpose two of the most important datasets for investigating Large Quasar Groups (LQGs) are the Sloan Digital Sky Survey (SDSS) and the 2dF Quasar Redshift Survey (2QZ). These have …
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Genome-scale metabolic modelling of Salmonella and Lactobacillus species
… on genomic and biochemical data obtained from public databases. A method for modelling metabolic interactions between cells was developed and applied to models of S. Typhimurium and the probiotic Lactobacillus plan-tarum, in order to simulate the intestinal stage of infection. The analysis …
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Protein Preservation in Fossil Whale Bones of the Miocene/Pliocene Pisco Formation, Peru
… to trypsin digested peptide patterns in the public databases. Nevertheless, it showed secondary fragmentation patterns (MS/MS) characteristic of peptidic material, which implies that it is composed of peptides, but these simply were not cleaved by trypsin, but rather by random (probably …
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