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Showing 1 to 2 of 2 for “"Public TCR"”.
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Autoimmune Susceptibility Imposed by Public TCRβ Chains
… It acts together with a corresponding TCR repertoire, yet, considering the extent of the repertoire's diversity, how this imposes disease susceptibility on a population is not well understood. We address the hypothesis that shared or public TCR, those present in most individuals, …
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Pathogenicity and Protection Mediated by a Single TCRβ in Experimental Autoimmune Encephalomyelitis
<p>How the TCR repertoire, together with risk-associated major histocompatibility complex (MHC), imposes susceptibility for autoimmune disease is not fully understood. A small fraction of TCR α or β chains are “public”, and are shared by most individuals.High-throughput sequencing of the mouse TCRβ …