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Showing 1 to 1 of 1 for “"Ptdss1"”.

  1. Loss of Ptdss1 in tumor cells improves anti-PD-1 therapy

    <p>PTDSS1 (Phosphatidylserine synthase 1) encodes an enzyme that facilitates production of phosphatidylserine (PS), which mediates a global immunosuppressive signal. Here, based on in vivo CRISPR screen, we identified PTDSS1 as a target to improve anti-PD-1 therapy. Depletion of PTDSS1 in tumor …

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