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Showing 1 to 1 of 1 for “"PtdIns(5)P"”.

  1. Molecular mechanisms of TOM1-mediated protein trafficking in health and disease

    … converts phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2] to phosphatidylinositol 5-phosphate [PtdIns(5)P]. The increase in PtdIns(5)P is thought to activate Na+/H+ exchange channels that pump H+ out of maturing endosomes. Rather than the lumen of the endosome acidifying, the endosome halts …

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